Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes

Choung Ryong Yoo; In Sung Yeo; Ko Eun Park; Ji Hun Park; Seung Jin Lee; Won Ho Park; Byung Moo Min

doi:10.1016/j.ijbiomac.2007.12.004

Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes

Choung Ryong Yoo
, In Sung Yeo
, Ko Eun Park
, Ji Hun Park
, Seung Jin Lee
, Won Ho Park
, Byung Moo Min

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

Abstract

To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.

Original language	English
Pages (from-to)	324-334
Number of pages	11
Journal	International Journal of Biological Macromolecules
Volume	42
Issue number	4
DOIs	https://doi.org/10.1016/j.ijbiomac.2007.12.004
State	Published - 1 May 2008

Bibliographical note

Funding Information:
This work was supported by a grant from the Korean Science and Engineering Foundation through the Intellectual Biointerface Engineering Center at Seoul National University and by a grant from the Korean Ministry of Commerce, Industry, and Energy.

Keywords

Electrospinning
Human epidermal keratinocytes
Nanofibrous scaffolds

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10.1016/j.ijbiomac.2007.12.004

Cite this

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title = "Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes",

abstract = "To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25\% chitin and 75\% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.",

keywords = "Electrospinning, Human epidermal keratinocytes, Nanofibrous scaffolds",

author = "Yoo, \{Choung Ryong\} and Yeo, \{In Sung\} and Park, \{Ko Eun\} and Park, \{Ji Hun\} and Lee, \{Seung Jin\} and Park, \{Won Ho\} and Min, \{Byung Moo\}",

note = "Funding Information: This work was supported by a grant from the Korean Science and Engineering Foundation through the Intellectual Biointerface Engineering Center at Seoul National University and by a grant from the Korean Ministry of Commerce, Industry, and Energy.",

year = "2008",

month = may,

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doi = "10.1016/j.ijbiomac.2007.12.004",

language = "English",

volume = "42",

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journal = "International Journal of Biological Macromolecules",

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AU - Yoo, Choung Ryong

AU - Yeo, In Sung

AU - Park, Ko Eun

AU - Park, Ji Hun

AU - Lee, Seung Jin

AU - Park, Won Ho

AU - Min, Byung Moo

N1 - Funding Information: This work was supported by a grant from the Korean Science and Engineering Foundation through the Intellectual Biointerface Engineering Center at Seoul National University and by a grant from the Korean Ministry of Commerce, Industry, and Energy.

PY - 2008/5/1

Y1 - 2008/5/1

N2 - To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.

AB - To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.

KW - Electrospinning

KW - Human epidermal keratinocytes

KW - Nanofibrous scaffolds

UR - https://www.scopus.com/pages/publications/41549148195

U2 - 10.1016/j.ijbiomac.2007.12.004

DO - 10.1016/j.ijbiomac.2007.12.004

M3 - Article

C2 - 18243300

AN - SCOPUS:41549148195

SN - 0141-8130

VL - 42

SP - 324

EP - 334

JO - International Journal of Biological Macromolecules

JF - International Journal of Biological Macromolecules

IS - 4

ER -

Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes

Abstract

Bibliographical note

Keywords

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