Dynamic Nanostructures from DNA-Coupled Molecules, Polymers, and Nanoparticles

Shine K. Albert, Xiaole Hu, So Jung Park

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Dynamic and reconfigurable systems that can sense and react to physical and chemical signals are ubiquitous in nature and are of great interest in diverse areas of science and technology. DNA is a powerful tool for fabricating such smart materials and devices due to its programmable and responsive molecular recognition properties. For the past couple of decades, DNA-based self-assembly is actively explored to fabricate various DNA–organic and DNA–inorganic hybrid nanostructures with high-precision structural control. Building upon past development, researchers have recently begun to design and assemble dynamic nanostructures that can undergo an on-demand transformation in the structure, properties, and motion in response to various external stimuli. In this Review, recent advances in dynamic DNA nanostructures, focusing on hybrid structures fabricated from DNA-conjugated molecules, polymers, and nanoparticles, are introduced, and their potential applications and future perspectives are discussed.

Original languageEnglish
Article number1900504
Issue number26
StatePublished - 26 Jun 2019

Bibliographical note

Publisher Copyright:
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim


  • DNA
  • DNA block copolymers
  • dynamic
  • nanoparticles
  • self-assembly
  • stimuli-responsive


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