Dual functions of nanoplasmonic optical antennas: Nanoplasmonic gene switches and biosensors

Somin Eunice Lee, Younggeun Park, Taewook Kang, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


Within a living cell, the intracellular distribution is spatially nonuniform and dynamically changing over time in response to environmental cues. By focusing on electromagnetic fields down to dimensions smaller than the diffraction limit, nanoplasmonic optical antennas, functioning as nanoplasmonic gene switches, enable on- demand and spatially precise regulation of genetic activity to give rise to location-specific function. In addition to on-demand gene regulation, nanoplasmonic optical antennas also function as label-free biosensors that significantly enhance spectral information for plasmon resonance energy transfer, surface-enhanced Raman spectroscopy, and nanoplasmonic molecular rulers. "Spectral snapshots" (i.e., spectroscopic imaging) of the dynamically changing intracellular biochemical distribution can be obtained over time.

Original languageEnglish
Title of host publicationNanoplasmonic Sensors
PublisherSpringer New York
Number of pages22
ISBN (Electronic)9781461439332
ISBN (Print)9781461439325
StatePublished - 1 Jan 2012

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2012. All rights are reserved.


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