The redox behavior of 'active aldehydes' 1- derived from 3-benzylthiazolium salts and simple aldehydes in the presence of a base has been examined with low temperature cyclic voltammetry and EPR spectroscopy. The highly negative oxidation potentials of 1- and the spin distribution of the intermediate radicals 1°indicate that the active aldehyde can act as an efficient electron mediator in thiamin-dependent enzymatic redox systems.
|Number of pages||3|
|Journal||Angewandte Chemie - International Edition|
|State||Published - 1998|
- Cyclic voltammetry
- EPR spectroscopy