Dihydroxylation of styrene by sodium chlorite with scandium triflate

Kei Ohkubo, Kensaku Hirose, Takekatsu Shibata, Kiyoto Takamori, Shunichi Fukuzumi

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8 Scopus citations


Dihydroxylation of styrene by chlorite (ClO2 ) with scandium triflate [Sc(OTf)3] occurs efficiently to produce 1-phenylethane-1,2-diol under the ambient conditions. Scandium triflate acting as a strong Lewis acid is found to accelerate the disproportionation of ClO2 to produce ClO and ClO3 . A scandium-chlorine dioxide complex (Sc3+ClO2 ) is generated by the reaction of ClO with ClO2 in the presence of Sc3 +. The binding of Sc3 + to ClO2 was detected by the electron paramagnetic resonance measurements, enhancing the reactivity and selectivity of styrene hydroxylation.

Original languageEnglish
Article numbere3619
JournalJournal of Physical Organic Chemistry
Issue number5
StatePublished - 1 May 2017

Bibliographical note

Publisher Copyright:
Copyright © 2016 John Wiley & Sons, Ltd.


  • Lewis acid
  • chlorine dioxide
  • chlorite
  • dihydroxylation
  • electron paramagnetic resonance


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