Differentiation of benign and malignant solid pseudopapillary neoplasms of the pancreas

Yong Eun Chung, Myeong Jin Kim, Jin Young Choi, Joon Seok Lim, Hye Suk Hong, Young Chul Kim, Hyeon Je Cho, Kyung Ah Kim, Sun Young Choi

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

OBJECTIVE: The aim of this study was to investigate differential imaging features between benign and malignant solid pseudopapillary neoplasms (SPN) of the pancreas on computed tomographic and magnetic resonance imagings. METHODS: Between January 2001 and January 2007, we identified 30 patients with confirmed SPN by surgery. The computed tomographic and magnetic resonance images were reviewed by 3 radiologists in consensus. Each tumor was analyzed for the following categories: location of tumor, tumor margin, proportion of solid component, morphology of capsule, growth pattern, calcification, and presence of upstream pancreatic ductal dilatation. RESULTS: Benign SPN usually had oval/round or smoothly lobulated margins, and malignant SPN more commonly had focal lobulated margins (P = 0.027). Presence of complete encapsulation was more frequently seen in benign SPN, whereas focal discontinuity of capsule was more commonly seen in malignant SPN (P = 0.005). There was no statistical difference between benign and malignant tumors in other imaging findings. CONCLUSIONS: A focal lobulated margin and a focal discontinuity of the capsule may suggest malignant SPN, whereas a round or smoothly lobulated margin and a complete encapsulation were more commonly seen in benign SPN.

Original languageEnglish
Pages (from-to)689-694
Number of pages6
JournalJournal of Computer Assisted Tomography
Volume33
Issue number5
DOIs
StatePublished - Sep 2009

Keywords

  • Computed tomography
  • Magnetic resonance imaging
  • Pancreatic neoplasm
  • Pathology
  • Solid pseudopapillary neoplasm

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