Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV Immunocompromised Patient in Korea: A Review and Algorithm Proposed by Expert Consensus Group

Raeseok Lee; Kyungmin Huh; Chang Kyung Kang; Yong Chan Kim; Jung Ho Kim; Hyungjin Kim; Jeong Su Park; Ji Young Park; Heungsup Sung; Jongtak Jung; Chung Jong Kim; Kyoung Ho Song

doi:10.3947/ic.2024.0148

Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV Immunocompromised Patient in Korea: A Review and Algorithm Proposed by Expert Consensus Group

Raeseok Lee, Kyungmin Huh, Chang Kyung Kang, Yong Chan Kim, Jung Ho Kim, Hyungjin Kim, Jeong Su Park, Ji Young Park, Heungsup Sung, Jongtak Jung, Chung Jong Kim, Kyoung Ho Song

Department of Internal Medicine

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Pneumocystis jirovecii pneumonia (PJP) is a life-threatening infection commonly observed in immunocompromised patients, necessitating prompt diagnosis and treatment. This review evaluates the diagnostic performance of various tests used for PJP diagnosis through a comprehensive literature review. Additionally, we propose a diagnostic algorithm tailored to non-human immunodeficiency virus immunocompromised patients, considering the specific characteristics of current medical resources in Korea.

Original language	English
Pages (from-to)	45-62
Number of pages	18
Journal	Infection and Chemotherapy
Volume	57
Issue number	1
DOIs	https://doi.org/10.3947/ic.2024.0148
State	Published - Mar 2025

Bibliographical note

Publisher Copyright:
© 2025 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, The Korean Society for AIDS, and Korean Society of Pediatric Infectious Diseases.

Keywords

Diagnosis
Pneumocystis jirovecii pneumonia
Polymerase chain reaction
β-D glucan

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3947/ic.2024.0148

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Lee, R., Huh, K., Kang, C. K., Kim, Y. C., Kim, J. H., Kim, H., Park, J. S., Park, J. Y., Sung, H., Jung, J., Kim, C. J., & Song, K. H. (2025). Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV Immunocompromised Patient in Korea: A Review and Algorithm Proposed by Expert Consensus Group. Infection and Chemotherapy, 57(1), 45-62. https://doi.org/10.3947/ic.2024.0148

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abstract = "Pneumocystis jirovecii pneumonia (PJP) is a life-threatening infection commonly observed in immunocompromised patients, necessitating prompt diagnosis and treatment. This review evaluates the diagnostic performance of various tests used for PJP diagnosis through a comprehensive literature review. Additionally, we propose a diagnostic algorithm tailored to non-human immunodeficiency virus immunocompromised patients, considering the specific characteristics of current medical resources in Korea.",

keywords = "Diagnosis, Pneumocystis jirovecii pneumonia, Polymerase chain reaction, β-D glucan",

author = "Raeseok Lee and Kyungmin Huh and Kang, {Chang Kyung} and Kim, {Yong Chan} and Kim, {Jung Ho} and Hyungjin Kim and Park, {Jeong Su} and Park, {Ji Young} and Heungsup Sung and Jongtak Jung and Kim, {Chung Jong} and Song, {Kyoung Ho}",

note = "Publisher Copyright: {\textcopyright} 2025 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, The Korean Society for AIDS, and Korean Society of Pediatric Infectious Diseases.",

year = "2025",

month = mar,

doi = "10.3947/ic.2024.0148",

language = "English",

volume = "57",

pages = "45--62",

journal = "Infection and Chemotherapy",

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T2 - A Review and Algorithm Proposed by Expert Consensus Group

AU - Lee, Raeseok

AU - Huh, Kyungmin

AU - Kang, Chang Kyung

AU - Kim, Yong Chan

AU - Kim, Jung Ho

AU - Kim, Hyungjin

AU - Park, Jeong Su

AU - Park, Ji Young

AU - Sung, Heungsup

AU - Jung, Jongtak

AU - Kim, Chung Jong

AU - Song, Kyoung Ho

N1 - Publisher Copyright: © 2025 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, The Korean Society for AIDS, and Korean Society of Pediatric Infectious Diseases.

PY - 2025/3

Y1 - 2025/3

N2 - Pneumocystis jirovecii pneumonia (PJP) is a life-threatening infection commonly observed in immunocompromised patients, necessitating prompt diagnosis and treatment. This review evaluates the diagnostic performance of various tests used for PJP diagnosis through a comprehensive literature review. Additionally, we propose a diagnostic algorithm tailored to non-human immunodeficiency virus immunocompromised patients, considering the specific characteristics of current medical resources in Korea.

AB - Pneumocystis jirovecii pneumonia (PJP) is a life-threatening infection commonly observed in immunocompromised patients, necessitating prompt diagnosis and treatment. This review evaluates the diagnostic performance of various tests used for PJP diagnosis through a comprehensive literature review. Additionally, we propose a diagnostic algorithm tailored to non-human immunodeficiency virus immunocompromised patients, considering the specific characteristics of current medical resources in Korea.

KW - Diagnosis

KW - Pneumocystis jirovecii pneumonia

KW - Polymerase chain reaction

KW - β-D glucan

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U2 - 10.3947/ic.2024.0148

DO - 10.3947/ic.2024.0148

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VL - 57

SP - 45

EP - 62

JO - Infection and Chemotherapy

JF - Infection and Chemotherapy

IS - 1

ER -

Diagnosis of Pneumocystis jirovecii Pneumonia in Non-HIV Immunocompromised Patient in Korea: A Review and Algorithm Proposed by Expert Consensus Group

Abstract

Bibliographical note

Keywords

UN SDGs

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