@inproceedings{a708ac476204469bbc1681c44d16832d,
title = "Detection of protein conformational changes with a nanogap biosensor",
abstract = "We demonstrate for the first time the detection of a conformational change in protein structure using a nanogap biosensor. Understanding the relationship between protein structure and function is paramount to unlocking life's processes on a molecular scale, and it is important to develop efficient measurement tools necessary to record these relationships. We have developed a unique nanoscale electrode-based biosensor that uses dielectric spectroscopy to interrogate samples inside a nanoscale gap, and we have shown that this biosensor is sensitive enough to record the conformational changes of a well known protein",
keywords = "Biosensor, Nanogap, Protein conformation",
author = "Nevill, {J. T.} and {Di Carlo}, D. and P. Liu and Jeong, {K. H.} and Lee, {L. P.}",
year = "2005",
doi = "10.1109/SENSOR.2005.1497410",
language = "English",
isbn = "0780389948",
series = "Digest of Technical Papers - International Conference on Solid State Sensors and Actuators and Microsystems, TRANSDUCERS '05",
pages = "1668--1671",
booktitle = "TRANSDUCERS '05 - 13th International Conference on Solid-State Sensors and Actuators and Microsystems - Digest of Technical Papers",
note = "13th International Conference on Solid-State Sensors and Actuators and Microsystems, TRANSDUCERS '05 ; Conference date: 05-06-2005 Through 09-06-2005",
}