@inproceedings{9d39b26e330c4f13bcceec7911f5276c,
title = "Dark-field smartphone microscope with nanoscale resolution for molecular diagnostics",
abstract = "Dark-field microscopy allows highly sensitive detection of metal nanoparticles that exhibit surface plasmon resonance (SPR) scattering by exclusively collecting scattered light. Here, we report a dark-field smartphone microscope with single nanoparticle resolution for point-of-care testing (POCT). A simple flat-lens LED is coupled to transparent substrate to generate total internal reflection (TIR) and evanescent field for surface-confined illumination, which scatters at nanoparticles. The scattering light is detected using smartphone camera through an external lens attachment. Dark-field smartphone microscope will facilitate the rapid translation of sensitive nanoparticle-based bioassays to point-of-care testing (POCT).",
keywords = "Dark-field microscopy, Nanoparticle, Point-of-care testing (POCT), Smartphone microscopy, Surface plasmon resonance (SPR), Total internal reflection (TIR)",
author = "Kim, {Brian N.} and Diaz, {Julian A.} and Hong, {Soon Gweon} and Lee, {Sang Hun} and Lee, {Luke P.}",
note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",
year = "2014",
language = "English",
series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
publisher = "Chemical and Biological Microsystems Society",
pages = "2247--2249",
booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
}