TY - JOUR
T1 - Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum
AU - Seo, Eun Kyoung
AU - Kim, Nam Cheol
AU - Wani, Mansukh C.
AU - Wall, Monroe E.
AU - Navarro, Hernán A.
AU - Burgess, Jason P.
AU - Kawanishi, Kazuko
AU - Kardono, Leonardus B.S.
AU - Riswan, Soedarsono
AU - Rose, William C.
AU - Fairchild, Craig R.
AU - Farnsworth, Norman R.
AU - Kinghorn, A. Douglas
PY - 2002
Y1 - 2002
N2 - Six new xanthones, cratoxyarborenones A-F (1-6), were isolated from the leaves, twigs, and/or stem bark of Cratoxylum sumatranum along with the known compound, vismione B (9), as active constituents by bioassay-directed fractionation using the KB human cancer cell line cytotoxicity assay. In addition, two novel anthraquinobenzophenones, cratoxyarborequinones A (7) and B (8), and two known compounds, 2,4,6-trihydroxybenzophenone 4-O-geranyl ether and δ-tocotrienol, were obtained as inactive constituents.
AB - Six new xanthones, cratoxyarborenones A-F (1-6), were isolated from the leaves, twigs, and/or stem bark of Cratoxylum sumatranum along with the known compound, vismione B (9), as active constituents by bioassay-directed fractionation using the KB human cancer cell line cytotoxicity assay. In addition, two novel anthraquinobenzophenones, cratoxyarborequinones A (7) and B (8), and two known compounds, 2,4,6-trihydroxybenzophenone 4-O-geranyl ether and δ-tocotrienol, were obtained as inactive constituents.
UR - http://www.scopus.com/inward/record.url?scp=0036193526&partnerID=8YFLogxK
U2 - 10.1021/np010395f
DO - 10.1021/np010395f
M3 - Article
C2 - 11908969
AN - SCOPUS:0036193526
SN - 0163-3864
VL - 65
SP - 299
EP - 305
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 3
ER -
