TY - JOUR
T1 - Customized valorization of waste streams by Pseudomonas putida
T2 - State-of-the-art, challenges, and future trends
AU - Son, Jina
AU - Lim, Seo Hyun
AU - Kim, Yu Jin
AU - Lim, Hye Jin
AU - Lee, Ji Yeon
AU - Jeong, Seona
AU - Park, Chulhwan
AU - Park, Si Jae
N1 - Publisher Copyright:
© 2023
PY - 2023/3
Y1 - 2023/3
N2 - Preventing catastrophic climate events warrants prompt action to delay global warming, which threatens health and food security. In this context, waste management using engineered microbes has emerged as a long-term eco-friendly solution for addressing the global climate crisis and transitioning to clean energy. Notably, Pseudomonas putida can valorize industry-derived synthetic wastes including plastics, oils, food, and agricultural waste into products of interest, and it has been extensively explored for establishing a fully circular bioeconomy through the conversion of waste into bio-based products, including platform chemicals (e.g., cis,cis-muconic and adipic acid) and biopolymers (e.g., medium-chain length polyhydroxyalkanoate). However, the efficiency of waste pretreatment technologies, capability of microbial cell factories, and practicability of synthetic biology tools remain low, posing a challenge to the industrial application of P. putida. The present review discusses the state-of-the-art, challenges, and future prospects for divergent biosynthesis of versatile products from waste-derived feedstocks using P. putida.
AB - Preventing catastrophic climate events warrants prompt action to delay global warming, which threatens health and food security. In this context, waste management using engineered microbes has emerged as a long-term eco-friendly solution for addressing the global climate crisis and transitioning to clean energy. Notably, Pseudomonas putida can valorize industry-derived synthetic wastes including plastics, oils, food, and agricultural waste into products of interest, and it has been extensively explored for establishing a fully circular bioeconomy through the conversion of waste into bio-based products, including platform chemicals (e.g., cis,cis-muconic and adipic acid) and biopolymers (e.g., medium-chain length polyhydroxyalkanoate). However, the efficiency of waste pretreatment technologies, capability of microbial cell factories, and practicability of synthetic biology tools remain low, posing a challenge to the industrial application of P. putida. The present review discusses the state-of-the-art, challenges, and future prospects for divergent biosynthesis of versatile products from waste-derived feedstocks using P. putida.
KW - Adipic acid
KW - Cis,cis-Muconic acid
KW - Mcl-PHA
KW - Pseudomonas putida
KW - Waste management
UR - http://www.scopus.com/inward/record.url?scp=85146161985&partnerID=8YFLogxK
U2 - 10.1016/j.biortech.2023.128607
DO - 10.1016/j.biortech.2023.128607
M3 - Article
C2 - 36638894
AN - SCOPUS:85146161985
SN - 0960-8524
VL - 371
JO - Bioresource Technology
JF - Bioresource Technology
M1 - 128607
ER -