CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Wonmok Lee; Hae Sun Chung; Hyukmin Lee; Jong Hwa Yum; Dongeun Yong; Seok Hoon Jeong; Kyungwon Lee; Yunsop Chong

doi:10.3343/alm.2013.33.2.141

CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Wonmok Lee, Hae Sun Chung, Hyukmin Lee, Jong Hwa Yum, Dongeun Yong, Seok Hoon Jeong, Kyungwon Lee, Yunsop Chong

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the bla_CTX-M-55 gene. The bla_CTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the bla_CTX-M-55 gene was located on a plasmid of approximately 130 kb.

Original language	English
Pages (from-to)	141-144
Number of pages	4
Journal	Annals of Laboratory Medicine
Volume	33
Issue number	2
DOIs	https://doi.org/10.3343/alm.2013.33.2.141
State	Published - 2013

Keywords

CTX-M-55
ESBL
Shigella sonnei

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title = "CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China",

abstract = "We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.",

keywords = "CTX-M-55, ESBL, Shigella sonnei",

author = "Wonmok Lee and Chung, \{Hae Sun\} and Hyukmin Lee and Yum, \{Jong Hwa\} and Dongeun Yong and Jeong, \{Seok Hoon\} and Kyungwon Lee and Yunsop Chong",

year = "2013",

doi = "10.3343/alm.2013.33.2.141",

language = "English",

volume = "33",

pages = "141--144",

journal = "Annals of Laboratory Medicine",

issn = "2234-3806",

publisher = "Korean Society for Laboratory Medicine",

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T1 - CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

AU - Lee, Wonmok

AU - Chung, Hae Sun

AU - Lee, Hyukmin

AU - Yum, Jong Hwa

AU - Yong, Dongeun

AU - Jeong, Seok Hoon

AU - Lee, Kyungwon

AU - Chong, Yunsop

PY - 2013

Y1 - 2013

N2 - We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.

AB - We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.

KW - CTX-M-55

KW - ESBL

KW - Shigella sonnei

UR - https://www.scopus.com/pages/publications/84876155234

U2 - 10.3343/alm.2013.33.2.141

DO - 10.3343/alm.2013.33.2.141

M3 - Article

C2 - 23483349

AN - SCOPUS:84876155234

SN - 2234-3806

VL - 33

SP - 141

EP - 144

JO - Annals of Laboratory Medicine

JF - Annals of Laboratory Medicine

IS - 2

ER -

CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Abstract

Keywords

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