CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Wonmok Lee; Hae Sun Chung; Hyukmin Lee; Jong Hwa Yum; Dongeun Yong; Seok Hoon Jeong; Kyungwon Lee; Yunsop Chong

doi:10.3343/alm.2013.33.2.141

CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Wonmok Lee
, Hae Sun Chung
, Hyukmin Lee
, Jong Hwa Yum
, Dongeun Yong
, Seok Hoon Jeong
, Kyungwon Lee
, Yunsop Chong

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the bla_CTX-M-55 gene. The bla_CTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the bla_CTX-M-55 gene was located on a plasmid of approximately 130 kb.

Original language	English
Pages (from-to)	141-144
Number of pages	4
Journal	Annals of Laboratory Medicine
Volume	33
Issue number	2
DOIs	https://doi.org/10.3343/alm.2013.33.2.141
State	Published - 2013

Keywords

CTX-M-55
ESBL
Shigella sonnei

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10.3343/alm.2013.33.2.141

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title = "CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China",

abstract = "We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.",

keywords = "CTX-M-55, ESBL, Shigella sonnei",

author = "Wonmok Lee and Chung, \{Hae Sun\} and Hyukmin Lee and Yum, \{Jong Hwa\} and Dongeun Yong and Jeong, \{Seok Hoon\} and Kyungwon Lee and Yunsop Chong",

year = "2013",

doi = "10.3343/alm.2013.33.2.141",

language = "English",

volume = "33",

pages = "141--144",

journal = "Annals of Laboratory Medicine",

issn = "2234-3806",

publisher = "Korean Society for Laboratory Medicine",

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TY - JOUR

T1 - CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

AU - Lee, Wonmok

AU - Chung, Hae Sun

AU - Lee, Hyukmin

AU - Yum, Jong Hwa

AU - Yong, Dongeun

AU - Jeong, Seok Hoon

AU - Lee, Kyungwon

AU - Chong, Yunsop

PY - 2013

Y1 - 2013

N2 - We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.

AB - We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3°C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.

KW - CTX-M-55

KW - ESBL

KW - Shigella sonnei

UR - https://www.scopus.com/pages/publications/84876155234

U2 - 10.3343/alm.2013.33.2.141

DO - 10.3343/alm.2013.33.2.141

M3 - Article

C2 - 23483349

AN - SCOPUS:84876155234

SN - 2234-3806

VL - 33

SP - 141

EP - 144

JO - Annals of Laboratory Medicine

JF - Annals of Laboratory Medicine

IS - 2

ER -

CTX-M-55-type extended-spectrum β-lactamase-producing Shigella sonnei isolated from a Korean patient who had travelled to China

Abstract

Keywords

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