TY - JOUR
T1 - Cross-sectional study estimating the psychosocial impact of genital warts and other anogenital diseases in South Korea
AU - Lee, Taek Sang
AU - Kothari-Talwar, Smita
AU - Singhal, Puneet K.
AU - Yee, Karen
AU - Kulkarni, Amit
AU - Lara, Nuria
AU - Roset, Montserrat
AU - Giuliano, Anna R.
AU - Garland, Suzanne M.
AU - Ju, Woong
N1 - Publisher Copyright:
© 2019 Author(s) (or their employer(s)). Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Objectives To estimate self-reported human papillomavirus (HPV) disease-related psychosocial impact among male and female patients in South Korea. Design In this multicentre cross-sectional study, psychosocial impacts were estimated using a one-time survey capturing HPV Impact Profile (HIP) results, CuestionarioEspecifico en Condilomas Acuminados (CECA; in Spanish)-Specific questionnaire for Condylomata Acuminata' and the EuroQol-5 Dimension (EQ-5D) surveys. Student's t-tests or Mann-Whitney U tests were used for continuous comparisons; 2 or Fisher's exact tests were applied for categorical comparisons. Setting 5098 clinics throughout Seoul, Busan, Daegu, Kwangju and Daejeon (South Korea). Participants Patients with and without genital warts (GW) (males) and selected HPV diseases (females) visiting primary care physicians, obstetricians/gynaecologists, urologists and dermatologists with 2-30 years experience. Results Of 150 male and 250 female patients, HIP scores showed 85.3% of male patients with GW and 32.0% without reported moderate psychological impact (p<0.0001). In categorised total scores, 88.5% of female patients with and 66.0% without selected HPV-related diseases reported moderate or high psychological impacts (p=0.0004). In the CECA questionnaire, male patients had mean (SD) scores of 10.51 (3.79) in emotional health' and 15.90 (6.13) in sexual activity'. Female patients with GW reported lower scores in both dimensions with mean scores of 7.18 (4.17) in emotional health' and 10.97 (5.80) in sexual activity' (p<0.0001), indicating worse health-related quality of life (HRQoL). For the EQ-5D, male patients with GW reported lower mean Visual Analogue Scale (VAS) scores than those without (75.1 vs 81.13, p<0.0135). Mean VAS score and utility values were lower for females with HPV-related diseases than those without (72.18 vs 76.86 and 0.90 vs 0.94, respectively). Conclusion In South Korea, GW in men and HPV-related diseases in women negatively impact patient well-being and HRQoL scores. Among women, those with GW suffered a greater psychosocial impact than those with other selected HPV-related diseases.
AB - Objectives To estimate self-reported human papillomavirus (HPV) disease-related psychosocial impact among male and female patients in South Korea. Design In this multicentre cross-sectional study, psychosocial impacts were estimated using a one-time survey capturing HPV Impact Profile (HIP) results, CuestionarioEspecifico en Condilomas Acuminados (CECA; in Spanish)-Specific questionnaire for Condylomata Acuminata' and the EuroQol-5 Dimension (EQ-5D) surveys. Student's t-tests or Mann-Whitney U tests were used for continuous comparisons; 2 or Fisher's exact tests were applied for categorical comparisons. Setting 5098 clinics throughout Seoul, Busan, Daegu, Kwangju and Daejeon (South Korea). Participants Patients with and without genital warts (GW) (males) and selected HPV diseases (females) visiting primary care physicians, obstetricians/gynaecologists, urologists and dermatologists with 2-30 years experience. Results Of 150 male and 250 female patients, HIP scores showed 85.3% of male patients with GW and 32.0% without reported moderate psychological impact (p<0.0001). In categorised total scores, 88.5% of female patients with and 66.0% without selected HPV-related diseases reported moderate or high psychological impacts (p=0.0004). In the CECA questionnaire, male patients had mean (SD) scores of 10.51 (3.79) in emotional health' and 15.90 (6.13) in sexual activity'. Female patients with GW reported lower scores in both dimensions with mean scores of 7.18 (4.17) in emotional health' and 10.97 (5.80) in sexual activity' (p<0.0001), indicating worse health-related quality of life (HRQoL). For the EQ-5D, male patients with GW reported lower mean Visual Analogue Scale (VAS) scores than those without (75.1 vs 81.13, p<0.0135). Mean VAS score and utility values were lower for females with HPV-related diseases than those without (72.18 vs 76.86 and 0.90 vs 0.94, respectively). Conclusion In South Korea, GW in men and HPV-related diseases in women negatively impact patient well-being and HRQoL scores. Among women, those with GW suffered a greater psychosocial impact than those with other selected HPV-related diseases.
KW - South Korea
KW - genital warts
KW - psychosocial impact
UR - http://www.scopus.com/inward/record.url?scp=85063282367&partnerID=8YFLogxK
U2 - 10.1136/bmjopen-2018-025035
DO - 10.1136/bmjopen-2018-025035
M3 - Article
C2 - 30898815
AN - SCOPUS:85063282367
SN - 2044-6055
VL - 9
JO - BMJ Open
JF - BMJ Open
IS - 3
M1 - e025035
ER -