TY - JOUR
T1 - Cooperative catalysis of a trinuclear ruthenium(II) complex in transfer hydrogenation of ketones by formic acid
AU - Yano, Yuichi
AU - Kojima, Takahiko
AU - Fukuzumi, Shunichi
N1 - Funding Information:
This work was supported by Grants-in-Aid (Nos. 21750146 , 21350035 and 20108010 ), a Global COE program, “the Global Education and Research Center for Bio-Environmental Chemistry” from the Japan Society of Promotion of Science (JSPS) , and by KOSEF/MEST through WCU project ( R31-2008-000-10010-0 ).
PY - 2011/8/1
Y1 - 2011/8/1
N2 - A novel TPA derivative (TPA = tris(2-pyridylmethyl)amine) having two 1,10-phenanthroline (phen) moieties via amide linkage was synthesized and this ligand reacted with [Ru(hmb)Cl2]2 (hmb: hexamethylbenzene) to give a trinuclear Ru(II) complex, [RuCl(TPA-{phenRuCl(hmb)} 2-H+)](PF6)2 (1-Cl), in a moderate yield. The complex involves a deprotonated and oxygen-coordinated amide linkage, which exhibits reversible protonation-deprotonation equilibrium. The chlorido complex was converted to be an aqua complex, [Ru(H2O)(TPA- {phenRu(H2O)2(hmb)}2-H+)](SO 4)5/2 (1-H2O), by the reaction of 1-Cl with Ag2SO4 in H2O. Transfer hydrogenation of ketones was examined by using 1-Cl as a catalyst and HCOONa as a hydride source in H2O/CH3OH (1:1 v/v) at 50 °C under Ar. The time-course of the transfer hydrogenation of cyclohexanone to give cyclohexanol revealed that 1-Cl showed a cooperative effect on the catalytic reactivity as compared with that of mononuclear [RuCl(hmb)(phen)] (3-Cl) and [RuCl((1-Naph)2-TPA)]PF6 in H2O/CH 3OH (1:2 v/v) under the same conditions. The detailed kinetic study has revealed that the catalytic transfer hydrogenation proceeds via the formato complex, which interacts with a substrate rather than via the hydrido complex. The two Ru centers placed at close proximity in 1-H2O enhanced the interaction of the formato complex with a substrate, resulting in an increase in the catalytic reactivity as compared with the mononuclear complex.
AB - A novel TPA derivative (TPA = tris(2-pyridylmethyl)amine) having two 1,10-phenanthroline (phen) moieties via amide linkage was synthesized and this ligand reacted with [Ru(hmb)Cl2]2 (hmb: hexamethylbenzene) to give a trinuclear Ru(II) complex, [RuCl(TPA-{phenRuCl(hmb)} 2-H+)](PF6)2 (1-Cl), in a moderate yield. The complex involves a deprotonated and oxygen-coordinated amide linkage, which exhibits reversible protonation-deprotonation equilibrium. The chlorido complex was converted to be an aqua complex, [Ru(H2O)(TPA- {phenRu(H2O)2(hmb)}2-H+)](SO 4)5/2 (1-H2O), by the reaction of 1-Cl with Ag2SO4 in H2O. Transfer hydrogenation of ketones was examined by using 1-Cl as a catalyst and HCOONa as a hydride source in H2O/CH3OH (1:1 v/v) at 50 °C under Ar. The time-course of the transfer hydrogenation of cyclohexanone to give cyclohexanol revealed that 1-Cl showed a cooperative effect on the catalytic reactivity as compared with that of mononuclear [RuCl(hmb)(phen)] (3-Cl) and [RuCl((1-Naph)2-TPA)]PF6 in H2O/CH 3OH (1:2 v/v) under the same conditions. The detailed kinetic study has revealed that the catalytic transfer hydrogenation proceeds via the formato complex, which interacts with a substrate rather than via the hydrido complex. The two Ru centers placed at close proximity in 1-H2O enhanced the interaction of the formato complex with a substrate, resulting in an increase in the catalytic reactivity as compared with the mononuclear complex.
KW - Catalysis
KW - Formic acid
KW - Ketones
KW - Ruthenium(II) complexes
KW - Transfer hydrogenation
UR - http://www.scopus.com/inward/record.url?scp=79960554540&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2011.01.100
DO - 10.1016/j.ica.2011.01.100
M3 - Article
AN - SCOPUS:79960554540
SN - 0020-1693
VL - 374
SP - 104
EP - 111
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
IS - 1
ER -