TY - GEN
T1 - Contractile force measurements of cardiac myocytes using a micro-manipulation system
AU - Park, Sukho
AU - Ryu, Seokchang
AU - Kim, Deok Ho
AU - Kim, Byungkyu
PY - 2005
Y1 - 2005
N2 - Recently, the microrobot powered by biological muscle actuators was proposed. The cell based actuator utilizes glucose as a power source and thus can apply to the application of a human body or blood vessels. For the structural design of the cell based micro-robot, the contractile force of the muscle powered by cardiac myocytes should be measured. In addition, the contractile force measurement can be used in the static or dynamic simulations of the micro-robot. In this paper, the contractile force measurement system, which is composed of a micro-manipulator, a force transducer, a signal processor and an inverted microscope is proposed. By using the measuring system, the contractile force for both control and micro-patterned cardiac myocytes are measured. From the experimental results, we estimated that the contractile force of cardiac myocytes is about 20-40 N when it is compared between the control cell and the cell on micro pattern.
AB - Recently, the microrobot powered by biological muscle actuators was proposed. The cell based actuator utilizes glucose as a power source and thus can apply to the application of a human body or blood vessels. For the structural design of the cell based micro-robot, the contractile force of the muscle powered by cardiac myocytes should be measured. In addition, the contractile force measurement can be used in the static or dynamic simulations of the micro-robot. In this paper, the contractile force measurement system, which is composed of a micro-manipulator, a force transducer, a signal processor and an inverted microscope is proposed. By using the measuring system, the contractile force for both control and micro-patterned cardiac myocytes are measured. From the experimental results, we estimated that the contractile force of cardiac myocytes is about 20-40 N when it is compared between the control cell and the cell on micro pattern.
KW - Cardiac myocytes
KW - Cell force measurement
KW - Micro-manipulation
KW - Piezo resistive sensor
UR - http://www.scopus.com/inward/record.url?scp=79958016375&partnerID=8YFLogxK
U2 - 10.1109/IROS.2005.1545019
DO - 10.1109/IROS.2005.1545019
M3 - Conference contribution
AN - SCOPUS:79958016375
SN - 0780389123
SN - 9780780389120
T3 - 2005 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS
SP - 2185
EP - 2190
BT - 2005 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS
PB - IEEE Computer Society
ER -