Abstract
In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.
Original language | English |
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Pages (from-to) | 203-207 |
Number of pages | 5 |
Journal | Brain Research |
Volume | 892 |
Issue number | 1 |
DOIs | |
State | Published - 16 Feb 2001 |
Keywords
- Brain
- In situ hybridization
- Rat
- Transcription factor
- c-myb