Constitutive expression of c-myb mRNA in the adult rat brain

Dong Hoon Shin, Hye Won Lee, Gye Sun Jeon, Hwa Young Lee, Kyung Hoon Lee, Sa Sun Cho

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.

Original languageEnglish
Pages (from-to)203-207
Number of pages5
JournalBrain Research
Volume892
Issue number1
DOIs
StatePublished - 16 Feb 2001

Keywords

  • Brain
  • c-myb
  • In situ hybridization
  • Rat
  • Transcription factor

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