@inproceedings{34f64a6cd5a94e9b885777248188cf4c,
title = "Comprehensive molecular profiling of single circulating tumor cells from lung cancer patients",
abstract = "There exists an urgent need for minimally invasive molecular analysis tools for cancer assessment and management, particularly in advanced-stage lung cancer, when tissue procurement is challenging and gene mutation profiling is crucial to identify molecularly targeted agents for treatment. High-throughput compartmentalization and multigene profiling of individual CTCs from whole blood samples using modular gene panels may facilitate highly sensitive, yet minimally-invasive characterization of lung cancer for therapy prediction and monitoring. We envision this nano-platform as a compelling research tool to investigate the dynamics of cancer disease processes, as well as a viable clinical platform for minimally-invasive yet comprehensive cancer assessment.",
keywords = "Circulating tumor cell, Gene expression, Magnetic separation, Microfluidic",
author = "Park, {Seung Min} and Wong, {Dawson J.} and Ooi, {Chin Chun} and Kurtz, {David M.} and Ophir Vermesh and Amin Aalipour and Susie Suh and Pian, {Kelsey L.} and Chabon, {Jacob J.} and Lee, {Sang Hun} and Mehran Jamali and Carmen Say and Carter, {Justin N.} and Lee, {Luke P.} and Kuschner, {Ware G.} and Schwartz, {Erich J.} and Shrager, {Joseph B.} and Neal, {Joel W.} and Wakelee, {Heather A.} and Maximilian Diehn and Nair, {Viswam S.} and Wang, {Shan X.} and Gambhir, {Sanjiv S.}",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "73--74",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}
