Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG

Jin Koo Kim; Jeong Hyun Kim; Seung Hwan Lee; Young Kang; Jong Seok Lim; Hee Gu Lee; Sang Jae Kim; Gill Han Bai; Young Kil Park; Sang Hyun Cho; Sang Won Kang; Yu Sam Kim; In Seong Choe; Tai Wha Chung; Sue Nie Park; Seung Ho Kim; Jong Seog Ahn; Yong Kyung Choe

doi:10.1080/15216549700202201

Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG

Jin Koo Kim, Jeong Hyun Kim, Seung Hwan Lee, Young Kang, Jong Seok Lim, Hee Gu Lee, Sang Jae Kim, Gill Han Bai, Young Kil Park, Sang Hyun Cho, Sang Won Kang, Yu Sam Kim, In Seong Choe, Tai Wha Chung, Sue Nie Park, Seung Ho Kim, Jong Seog Ahn, Yong Kyung Choe

Department of Life Science

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The nucleotide sequence of a 799 bp fragment of Mycobacterium bovis BCG containing the putative upp gene that encodes a uracil phosphoribosyltransferase (UPRTase [EC 2.4.2.9]) has been determined. The upp gene of BCG has an open reading frame (ORF) of 621 bp (207 amino acids) starting with GTG (position 112) and ending with TGA (position 733), and its molecular mass was calculated to be 21,864 Da. Comparative analyses of the deduced amino acid sequence of BCG UPRTase with the UPRTase of six bacterial genera revealed that 24% (50/211) of die residues are perfectly conserved and 32% (67/211) of the residues are well conserved.

Original language	English
Pages (from-to)	1117-1124
Number of pages	8
Journal	Biochemistry and Molecular Biology International
Volume	41
Issue number	6
DOIs	https://doi.org/10.1080/15216549700202201
State	Published - May 1997

Keywords

BCG
Uracil phosphoribosyltraltsferase
upp

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Kim, J. K., Kim, J. H., Lee, S. H., Kang, Y., Lim, J. S., Lee, H. G., Kim, S. J., Bai, G. H., Park, Y. K., Cho, S. H., Kang, S. W., Kim, Y. S., Choe, I. S., Chung, T. W., Park, S. N., Kim, S. H., Ahn, J. S., & Choe, Y. K. (1997). Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG. Biochemistry and Molecular Biology International, 41(6), 1117-1124. https://doi.org/10.1080/15216549700202201

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title = "Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG",

abstract = "The nucleotide sequence of a 799 bp fragment of Mycobacterium bovis BCG containing the putative upp gene that encodes a uracil phosphoribosyltransferase (UPRTase [EC 2.4.2.9]) has been determined. The upp gene of BCG has an open reading frame (ORF) of 621 bp (207 amino acids) starting with GTG (position 112) and ending with TGA (position 733), and its molecular mass was calculated to be 21,864 Da. Comparative analyses of the deduced amino acid sequence of BCG UPRTase with the UPRTase of six bacterial genera revealed that 24% (50/211) of die residues are perfectly conserved and 32% (67/211) of the residues are well conserved.",

keywords = "BCG, Uracil phosphoribosyltraltsferase, upp",

author = "Kim, {Jin Koo} and Kim, {Jeong Hyun} and Lee, {Seung Hwan} and Young Kang and Lim, {Jong Seok} and Lee, {Hee Gu} and Kim, {Sang Jae} and Bai, {Gill Han} and Park, {Young Kil} and Cho, {Sang Hyun} and Kang, {Sang Won} and Kim, {Yu Sam} and Choe, {In Seong} and Chung, {Tai Wha} and Park, {Sue Nie} and Kim, {Seung Ho} and Ahn, {Jong Seog} and Choe, {Yong Kyung}",

year = "1997",

month = may,

doi = "10.1080/15216549700202201",

language = "English",

volume = "41",

pages = "1117--1124",

journal = "Biochemistry and Molecular Biology International",

issn = "1039-9712",

publisher = "Academic Press Inc.",

number = "6",

}

Kim, JK, Kim, JH, Lee, SH, Kang, Y, Lim, JS, Lee, HG, Kim, SJ, Bai, GH, Park, YK, Cho, SH, Kang, SW, Kim, YS, Choe, IS, Chung, TW, Park, SN, Kim, SH, Ahn, JS & Choe, YK 1997, 'Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG', Biochemistry and Molecular Biology International, vol. 41, no. 6, pp. 1117-1124. https://doi.org/10.1080/15216549700202201

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T1 - Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG

AU - Kim, Jin Koo

AU - Kim, Jeong Hyun

AU - Lee, Seung Hwan

AU - Kang, Young

AU - Lim, Jong Seok

AU - Lee, Hee Gu

AU - Kim, Sang Jae

AU - Bai, Gill Han

AU - Park, Young Kil

AU - Cho, Sang Hyun

AU - Kang, Sang Won

AU - Kim, Yu Sam

AU - Choe, In Seong

AU - Chung, Tai Wha

AU - Park, Sue Nie

AU - Kim, Seung Ho

AU - Ahn, Jong Seog

AU - Choe, Yong Kyung

PY - 1997/5

Y1 - 1997/5

N2 - The nucleotide sequence of a 799 bp fragment of Mycobacterium bovis BCG containing the putative upp gene that encodes a uracil phosphoribosyltransferase (UPRTase [EC 2.4.2.9]) has been determined. The upp gene of BCG has an open reading frame (ORF) of 621 bp (207 amino acids) starting with GTG (position 112) and ending with TGA (position 733), and its molecular mass was calculated to be 21,864 Da. Comparative analyses of the deduced amino acid sequence of BCG UPRTase with the UPRTase of six bacterial genera revealed that 24% (50/211) of die residues are perfectly conserved and 32% (67/211) of the residues are well conserved.

AB - The nucleotide sequence of a 799 bp fragment of Mycobacterium bovis BCG containing the putative upp gene that encodes a uracil phosphoribosyltransferase (UPRTase [EC 2.4.2.9]) has been determined. The upp gene of BCG has an open reading frame (ORF) of 621 bp (207 amino acids) starting with GTG (position 112) and ending with TGA (position 733), and its molecular mass was calculated to be 21,864 Da. Comparative analyses of the deduced amino acid sequence of BCG UPRTase with the UPRTase of six bacterial genera revealed that 24% (50/211) of die residues are perfectly conserved and 32% (67/211) of the residues are well conserved.

KW - BCG

KW - Uracil phosphoribosyltraltsferase

KW - upp

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AN - SCOPUS:17144473004

SN - 1039-9712

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EP - 1124

JO - Biochemistry and Molecular Biology International

JF - Biochemistry and Molecular Biology International

IS - 6

ER -

Complete sequence of the upp gene encoding uracil phosphoribosyltransferase from mycobacterium bovis BCG

Abstract

Keywords

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