Comparison of the SRmax, SRave, and color map of strain-elastography in differentiating malignant from benign breast lesions

Jin Hee Moon; Sung Hye Koh; Sun Young Park; Ji Young Hwang; Ji Young Woo

doi:10.1177/0284185118773510

Comparison of the SR_max, SR_ave, and color map of strain-elastography in differentiating malignant from benign breast lesions

Jin Hee Moon, Sung Hye Koh, Sun Young Park, Ji Young Hwang, Ji Young Woo

Department of Radiology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Background: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. Purpose: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SR_max), the average value of the SR (SR_ave), and the color map, for differentiating benign and malignant breast lesions. Material and Methods: We obtained the SR_max and SR_ave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SR_max, SR_ave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. Results: The AUC of the SR_max (0.7674) was larger than the AUCs of the SR_ave (0.7138) and color map (0.6324), with statistical significance (P = 0.0383 for SR_max vs. SR_ave, P = 0.0000 for SR_max vs. color map). The AUC of the SR_ave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SR_max that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. Conclusion: The SR_max is a more reliable diagnostic tool than the SR_ave and color map for differentiating benign and malignant breast lesions.

Original language	English
Pages (from-to)	28-34
Number of pages	7
Journal	Acta Radiologica
Volume	60
Issue number	1
DOIs	https://doi.org/10.1177/0284185118773510
State	Published - 1 Jan 2019

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by Hallym University Research Fund 2017 (HURF-2017-14).

Publisher Copyright:
© The Foundation Acta Radiologica 2018.

Keywords

Breast
solid mass
strain ratio
strain-elastography
ultrasound

Access to Document

10.1177/0284185118773510

Cite this

@article{ff5d6366307345cfb2ed275e607fe385,

title = "Comparison of the SRmax, SRave, and color map of strain-elastography in differentiating malignant from benign breast lesions",

abstract = "Background: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. Purpose: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SRmax), the average value of the SR (SRave), and the color map, for differentiating benign and malignant breast lesions. Material and Methods: We obtained the SRmax and SRave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SRmax, SRave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. Results: The AUC of the SRmax (0.7674) was larger than the AUCs of the SRave (0.7138) and color map (0.6324), with statistical significance (P = 0.0383 for SRmax vs. SRave, P = 0.0000 for SRmax vs. color map). The AUC of the SRave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SRmax that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. Conclusion: The SRmax is a more reliable diagnostic tool than the SRave and color map for differentiating benign and malignant breast lesions.",

keywords = "Breast, solid mass, strain ratio, strain-elastography, ultrasound",

author = "Moon, {Jin Hee} and Koh, {Sung Hye} and Park, {Sun Young} and Hwang, {Ji Young} and Woo, {Ji Young}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by Hallym University Research Fund 2017 (HURF-2017-14). Publisher Copyright: {\textcopyright} The Foundation Acta Radiologica 2018.",

year = "2019",

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doi = "10.1177/0284185118773510",

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T1 - Comparison of the SRmax, SRave, and color map of strain-elastography in differentiating malignant from benign breast lesions

AU - Moon, Jin Hee

AU - Koh, Sung Hye

AU - Park, Sun Young

AU - Hwang, Ji Young

AU - Woo, Ji Young

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by Hallym University Research Fund 2017 (HURF-2017-14). Publisher Copyright: © The Foundation Acta Radiologica 2018.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. Purpose: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SRmax), the average value of the SR (SRave), and the color map, for differentiating benign and malignant breast lesions. Material and Methods: We obtained the SRmax and SRave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SRmax, SRave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. Results: The AUC of the SRmax (0.7674) was larger than the AUCs of the SRave (0.7138) and color map (0.6324), with statistical significance (P = 0.0383 for SRmax vs. SRave, P = 0.0000 for SRmax vs. color map). The AUC of the SRave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SRmax that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. Conclusion: The SRmax is a more reliable diagnostic tool than the SRave and color map for differentiating benign and malignant breast lesions.

AB - Background: The maximum value of the strain ratio (SR) is a newly developed measure in strain-elastography. Purpose: To prospectively compare the diagnostic performance of three different measures of strain-elastography, the maximum value of the SR (SRmax), the average value of the SR (SRave), and the color map, for differentiating benign and malignant breast lesions. Material and Methods: We obtained the SRmax and SRave of 314 lesions from 290 patients with the tissue to nodule SR and color map using a five-degree scoring system. The diagnostic performances of the SRmax, SRave, and color map were compared after obtaining the area under the receiver operating characteristic (ROC) curves (AUCs) of each parameter. Results: The AUC of the SRmax (0.7674) was larger than the AUCs of the SRave (0.7138) and color map (0.6324), with statistical significance (P = 0.0383 for SRmax vs. SRave, P = 0.0000 for SRmax vs. color map). The AUC of the SRave was larger than that of the color map; however, there was no significant difference. The optimal cut-off point of the SRmax that balanced the sensitivity (91.12%) and specificity (50.81%) was 5.16. Conclusion: The SRmax is a more reliable diagnostic tool than the SRave and color map for differentiating benign and malignant breast lesions.

KW - Breast

KW - solid mass

KW - strain ratio

KW - strain-elastography

KW - ultrasound

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