Comparison of subjective quality of life after endoscopic submucosal resection or surgery for early gastric cancer

Chung Hyun Tae, Ki Nam Shim, Byung Wook Kim, Jie Hyun Kim, Su Jin Hong, Gwang Ho Baik, Hyun Joo Song, Yong Sung Kim, Seung Ho Jang, Hye Kyung Jung

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5 Scopus citations

Abstract

Quality of life (QoL) has become an important issue after early gastric cancer (EGC) treatment. We aimed to compare the QoL of EGC survivors after ESD (n = 241) or laparoscopic subtotal gastrectomy (n = 241) without recurrence and to evaluate the QoL over the 5-year period after adjusting for various confounding factors related to QoL. QoL related to the gastric cancer subscale (GCS) was significantly higher in the ESD group than surgery group (p < 0.001). After adjusting for all possible confounding factors, survivors who underwent ESD still had higher QoL related to CSG than those who underwent surgery. On the analysis of interaction effects for all QoL subscales, higher QoL related to GCS of ESD group than those of surgery group has been kept over time (p = 0.983). Therefore, we concluded that EGC survivors who undergo ESD have significantly better QoL related to GCS over a 5-year period after treatment than those who undergo surgery. This may be a useful consideration when selecting treatment modalities for patients with EGC.

Original languageEnglish
Article number6680
JournalScientific Reports
Volume10
Issue number1
DOIs
StatePublished - 1 Dec 2020

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