Comparison of subjective quality of life after endoscopic submucosal resection or surgery for early gastric cancer

Chung Hyun Tae; Ki Nam Shim; Byung Wook Kim; Jie Hyun Kim; Su Jin Hong; Gwang Ho Baik; Hyun Joo Song; Yong Sung Kim; Seung Ho Jang; Hye Kyung Jung

doi:10.1038/s41598-020-62854-7

Comparison of subjective quality of life after endoscopic submucosal resection or surgery for early gastric cancer

Chung Hyun Tae, Ki Nam Shim, Byung Wook Kim, Jie Hyun Kim, Su Jin Hong, Gwang Ho Baik, Hyun Joo Song, Yong Sung Kim, Seung Ho Jang, Hye Kyung Jung

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Quality of life (QoL) has become an important issue after early gastric cancer (EGC) treatment. We aimed to compare the QoL of EGC survivors after ESD (n = 241) or laparoscopic subtotal gastrectomy (n = 241) without recurrence and to evaluate the QoL over the 5-year period after adjusting for various confounding factors related to QoL. QoL related to the gastric cancer subscale (GCS) was significantly higher in the ESD group than surgery group (p < 0.001). After adjusting for all possible confounding factors, survivors who underwent ESD still had higher QoL related to CSG than those who underwent surgery. On the analysis of interaction effects for all QoL subscales, higher QoL related to GCS of ESD group than those of surgery group has been kept over time (p = 0.983). Therefore, we concluded that EGC survivors who undergo ESD have significantly better QoL related to GCS over a 5-year period after treatment than those who undergo surgery. This may be a useful consideration when selecting treatment modalities for patients with EGC.

Original language	English
Article number	6680
Journal	Scientific Reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-62854-7
State	Published - 1 Dec 2020

Bibliographical note

Funding Information:
This study was funded by the Korean College of Helicobacter and Upper Gastrointestinal Research.

Publisher Copyright:
© 2020, The Author(s).

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title = "Comparison of subjective quality of life after endoscopic submucosal resection or surgery for early gastric cancer",

abstract = "Quality of life (QoL) has become an important issue after early gastric cancer (EGC) treatment. We aimed to compare the QoL of EGC survivors after ESD (n = 241) or laparoscopic subtotal gastrectomy (n = 241) without recurrence and to evaluate the QoL over the 5-year period after adjusting for various confounding factors related to QoL. QoL related to the gastric cancer subscale (GCS) was significantly higher in the ESD group than surgery group (p < 0.001). After adjusting for all possible confounding factors, survivors who underwent ESD still had higher QoL related to CSG than those who underwent surgery. On the analysis of interaction effects for all QoL subscales, higher QoL related to GCS of ESD group than those of surgery group has been kept over time (p = 0.983). Therefore, we concluded that EGC survivors who undergo ESD have significantly better QoL related to GCS over a 5-year period after treatment than those who undergo surgery. This may be a useful consideration when selecting treatment modalities for patients with EGC.",

author = "Tae, {Chung Hyun} and Shim, {Ki Nam} and Kim, {Byung Wook} and Kim, {Jie Hyun} and Hong, {Su Jin} and Baik, {Gwang Ho} and Song, {Hyun Joo} and Kim, {Yong Sung} and Jang, {Seung Ho} and Jung, {Hye Kyung}",

note = "Funding Information: This study was funded by the Korean College of Helicobacter and Upper Gastrointestinal Research. Publisher Copyright: {\textcopyright} 2020, The Author(s).",

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AU - Hong, Su Jin

AU - Baik, Gwang Ho

AU - Song, Hyun Joo

AU - Kim, Yong Sung

AU - Jang, Seung Ho

AU - Jung, Hye Kyung

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N2 - Quality of life (QoL) has become an important issue after early gastric cancer (EGC) treatment. We aimed to compare the QoL of EGC survivors after ESD (n = 241) or laparoscopic subtotal gastrectomy (n = 241) without recurrence and to evaluate the QoL over the 5-year period after adjusting for various confounding factors related to QoL. QoL related to the gastric cancer subscale (GCS) was significantly higher in the ESD group than surgery group (p < 0.001). After adjusting for all possible confounding factors, survivors who underwent ESD still had higher QoL related to CSG than those who underwent surgery. On the analysis of interaction effects for all QoL subscales, higher QoL related to GCS of ESD group than those of surgery group has been kept over time (p = 0.983). Therefore, we concluded that EGC survivors who undergo ESD have significantly better QoL related to GCS over a 5-year period after treatment than those who undergo surgery. This may be a useful consideration when selecting treatment modalities for patients with EGC.

AB - Quality of life (QoL) has become an important issue after early gastric cancer (EGC) treatment. We aimed to compare the QoL of EGC survivors after ESD (n = 241) or laparoscopic subtotal gastrectomy (n = 241) without recurrence and to evaluate the QoL over the 5-year period after adjusting for various confounding factors related to QoL. QoL related to the gastric cancer subscale (GCS) was significantly higher in the ESD group than surgery group (p < 0.001). After adjusting for all possible confounding factors, survivors who underwent ESD still had higher QoL related to CSG than those who underwent surgery. On the analysis of interaction effects for all QoL subscales, higher QoL related to GCS of ESD group than those of surgery group has been kept over time (p = 0.983). Therefore, we concluded that EGC survivors who undergo ESD have significantly better QoL related to GCS over a 5-year period after treatment than those who undergo surgery. This may be a useful consideration when selecting treatment modalities for patients with EGC.

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Comparison of subjective quality of life after endoscopic submucosal resection or surgery for early gastric cancer

Abstract

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