Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

Won Joo Kwon; Joo Yeon Ko; Young Suck Ro; Myung Hwa Kim; Byung Soo Kim; Hye One Kim; Jae Hui Nam; Ga Young Lee; Mi Youn Park; Sang Wook Son; Jun Mo Yang; Dong Hun Lee; Ai Young Lee; Jun Young Lee; Sung Eun Chang; Hae Young Choi; Eun Joo Park

doi:10.1684/ejd.2017.3139

Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

Won Joo Kwon, Joo Yeon Ko, Young Suck Ro, Myung Hwa Kim, Byung Soo Kim, Hye One Kim, Jae Hui Nam, Ga Young Lee, Mi Youn Park, Sang Wook Son, Jun Mo Yang, Dong Hun Lee, Ai Young Lee, Jun Young Lee, Sung Eun Chang, Hae Young Choi, Eun Joo Park

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Background: A comparison between responses to allergens based on the TRUE Test®(TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. Objectives: To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Materials & methods: Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. Results: The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. Conclusions: We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

Original language	English
Pages (from-to)	573-578
Number of pages	6
Journal	European Journal of Dermatology
Volume	27
Issue number	6
DOIs	https://doi.org/10.1684/ejd.2017.3139
State	Published - 1 Nov 2017

Keywords

Concordance
IQ® Chamber
Korean standard series
Patch test
TRUE Test®

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10.1684/ejd.2017.3139

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Kwon, W. J., Ko, J. Y., Ro, Y. S., Kim, M. H., Kim, B. S., Kim, H. O., Nam, J. H., Lee, G. Y., Park, M. Y., Son, S. W., Yang, J. M., Lee, D. H., Lee, A. Y., Lee, J. Y., Chang, S. E., Choi, H. Y., & Park, E. J. (2017). Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients. European Journal of Dermatology, 27(6), 573-578. https://doi.org/10.1684/ejd.2017.3139

@article{4378efc997b0457b9d8414362dd4e567,

title = "Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients",

abstract = "Background: A comparison between responses to allergens based on the TRUE Test{\textregistered}(TT) and IQ{\textregistered} Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. Objectives: To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Materials & methods: Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. Results: The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. Conclusions: We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.",

keywords = "Concordance, IQ{\textregistered} Chamber, Korean standard series, Patch test, TRUE Test{\textregistered}",

author = "Kwon, {Won Joo} and Ko, {Joo Yeon} and Ro, {Young Suck} and Kim, {Myung Hwa} and Kim, {Byung Soo} and Kim, {Hye One} and Nam, {Jae Hui} and Lee, {Ga Young} and Park, {Mi Youn} and Son, {Sang Wook} and Yang, {Jun Mo} and Lee, {Dong Hun} and Lee, {Ai Young} and Lee, {Jun Young} and Chang, {Sung Eun} and Choi, {Hae Young} and Park, {Eun Joo}",

note = "Funding Information: Disclosure. Financial support: this research was funded by the Korean Dermatological Association (KDA). Conflict of interest: none. Publisher Copyright: {\textcopyright} 2017, John Libbey Eurotext. All rights reserved.",

year = "2017",

month = nov,

day = "1",

doi = "10.1684/ejd.2017.3139",

language = "English",

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journal = "European Journal of Dermatology",

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T1 - Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

AU - Kwon, Won Joo

AU - Ko, Joo Yeon

AU - Ro, Young Suck

AU - Kim, Myung Hwa

AU - Kim, Byung Soo

AU - Kim, Hye One

AU - Nam, Jae Hui

AU - Lee, Ga Young

AU - Park, Mi Youn

AU - Son, Sang Wook

AU - Yang, Jun Mo

AU - Lee, Dong Hun

AU - Lee, Ai Young

AU - Lee, Jun Young

AU - Chang, Sung Eun

AU - Choi, Hae Young

AU - Park, Eun Joo

N1 - Funding Information: Disclosure. Financial support: this research was funded by the Korean Dermatological Association (KDA). Conflict of interest: none. Publisher Copyright: © 2017, John Libbey Eurotext. All rights reserved.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Background: A comparison between responses to allergens based on the TRUE Test®(TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. Objectives: To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Materials & methods: Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. Results: The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. Conclusions: We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

AB - Background: A comparison between responses to allergens based on the TRUE Test®(TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. Objectives: To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Materials & methods: Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. Results: The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. Conclusions: We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

KW - Concordance

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KW - Korean standard series

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KW - TRUE Test®

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AN - SCOPUS:85040459737

SN - 1167-1122

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JO - European Journal of Dermatology

JF - European Journal of Dermatology

IS - 6

ER -

Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

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Keywords

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