Comparison between MRI with MR cholangiopancreatography and endoscopic ultrasonography for differentiating malignant from benign mucinous neoplasms of the pancreas

Jiyoung Hwang, Young Kon Kim, Ji Hye Min, Woo Kyung Jeong, Seong Sook Hong, Hyun joo Kim

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Objective: To compare diagnostic performance of magnetic resonance imaging (MRI) and endoscopic ultrasonography (EUS) for differentiating malignant from benign intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN) of the pancreas. Methods: This retrospective study included 55 patients with 47 surgically confirmed IPMNs (12 malignant, 35 benign) and eight MCNs (two malignant, six benign) who underwent contrast-enhanced pancreas MRI and EUS. Contrast enhancement was not routinely used at EUS examination. Two observers independently evaluated the MRIs, and another reviewed EUS images. They recorded their confidence for malignancy with each imaging modality. We calculated diagnostic performance using the area under the receiver operating characteristic curves (Az), and to determine the accuracy, sensitivity, specificity, and positive (PPV) and negative predictive (NPV) values. Results: The Az values of MRI were higher than those of EUS (0.712 and 0.688 for MRI vs. 0.543 for EUS; p = 0.007). The diagnostic accuracies (74.5%), specificity (78.0% and 80.5%) and PPV (50.0%) of MRI in two observers were higher than those (56.4%, 58.5% and 29.2%, respectively) of EUS (p = 0.013–0.049). Conclusion: MRI showed better diagnostic performance than EUS for differentiating malignant from benign pancreatic IPMN and MCN. Key Points: • The Azvalues of MRI were higher than those of EUS. • The diagnostic accuracies of MRI were higher than those of EUS. • The specificities of MRI were higher than those of EUS.

Original languageEnglish
Pages (from-to)179-187
Number of pages9
JournalEuropean Radiology
Volume28
Issue number1
DOIs
StatePublished - 1 Jan 2018

Bibliographical note

Publisher Copyright:
© 2017, European Society of Radiology.

Keywords

  • Endoscopic ultrasonography
  • Intraductal papillary mucinous neoplasm
  • Magnetic resonance imaging
  • Mucinous cystic neoplasm
  • Mural nodule

Fingerprint

Dive into the research topics of 'Comparison between MRI with MR cholangiopancreatography and endoscopic ultrasonography for differentiating malignant from benign mucinous neoplasms of the pancreas'. Together they form a unique fingerprint.

Cite this