Comparative Study in Different Filters for Efficient Sterile Filtration

Hyun Ho An; Byung Seok Moon; Hyun Sik Park; Hong Jin Lee; Sang Ju Lee; Seung Jun Oh; Bom Sahn Kim; Byung Chul Lee; Won Woo Lee; Sang Eun Kim

doi:10.1002/bkcs.12073

Comparative Study in Different Filters for Efficient Sterile Filtration

Hyun Ho An, Byung Seok Moon, Hyun Sik Park, Hong Jin Lee, Sang Ju Lee, Seung Jun Oh, Bom Sahn Kim, Byung Chul Lee, Won Woo Lee, Sang Eun Kim

Department of Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

Original language	English
Pages (from-to)	824-828
Number of pages	5
Journal	Bulletin of the Korean Chemical Society
Volume	41
Issue number	8
DOIs	https://doi.org/10.1002/bkcs.12073
State	Published - 1 Aug 2020

Bibliographical note

Publisher Copyright:
© 2020 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

C-Pittsburgh compound B
Positron emission tomography
Radiopharmaceuticals
Sterile membrane filtration

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10.1002/bkcs.12073

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title = "Comparative Study in Different Filters for Efficient Sterile Filtration",

abstract = "Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.",

keywords = "C-Pittsburgh compound B, Positron emission tomography, Radiopharmaceuticals, Sterile membrane filtration",

author = "An, \{Hyun Ho\} and Moon, \{Byung Seok\} and Park, \{Hyun Sik\} and Lee, \{Hong Jin\} and Lee, \{Sang Ju\} and Oh, \{Seung Jun\} and Kim, \{Bom Sahn\} and Lee, \{Byung Chul\} and Lee, \{Won Woo\} and Kim, \{Sang Eun\}",

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doi = "10.1002/bkcs.12073",

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TY - JOUR

T1 - Comparative Study in Different Filters for Efficient Sterile Filtration

AU - An, Hyun Ho

AU - Moon, Byung Seok

AU - Park, Hyun Sik

AU - Lee, Hong Jin

AU - Lee, Sang Ju

AU - Oh, Seung Jun

AU - Kim, Bom Sahn

AU - Lee, Byung Chul

AU - Lee, Won Woo

AU - Kim, Sang Eun

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

AB - Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

KW - C-Pittsburgh compound B

KW - Positron emission tomography

KW - Radiopharmaceuticals

KW - Sterile membrane filtration

UR - https://www.scopus.com/pages/publications/85088698970

U2 - 10.1002/bkcs.12073

DO - 10.1002/bkcs.12073

M3 - Article

AN - SCOPUS:85088698970

SN - 0253-2964

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SP - 824

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JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 8

ER -

Comparative Study in Different Filters for Efficient Sterile Filtration

Abstract

Bibliographical note

Keywords

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