Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.
Bibliographical notePublisher Copyright:
© 2020 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
- C-Pittsburgh compound B
- Positron emission tomography
- Sterile membrane filtration