Comparative Study in Different Filters for Efficient Sterile Filtration

Hyun Ho An, Byung Seok Moon, Hyun Sik Park, Hong Jin Lee, Sang Ju Lee, Seung Jun Oh, Bom Sahn Kim, Byung Chul Lee, Won Woo Lee, Sang Eun Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half-life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

Original languageEnglish
Pages (from-to)824-828
Number of pages5
JournalBulletin of the Korean Chemical Society
Volume41
Issue number8
DOIs
StatePublished - 1 Aug 2020

Keywords

  • C-Pittsburgh compound B
  • Positron emission tomography
  • Radiopharmaceuticals
  • Sterile membrane filtration

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