TY - GEN
T1 - Comparative quantification of contractile force of cardiac muscle using a micro-mechanical cell force measurement system
AU - Ryu, Seokchang
AU - Kim, Byungkyu
AU - Kim, Deokho
AU - Park, Sukho
PY - 2005
Y1 - 2005
N2 - In order to develop the cell based robot, we presented a micro-mechanical force measurement system for the biological muscle actuators, which utilize glucose as a power source for potential application in digestive organ. The proposed system is composed of a micro-manipulator, a force transducer with a glass probe, a signal processor, an inverted microscope and video recoding system. Using this measurement system, the contractile force and frequency of the cardiac myocytes were measured in real time and the magnitudes of the contractile force of each cardiac myocyte under different conditions were compared. From the quantitative experimental results, we could estimate that the force of cardiac myocytes is about 20-40 μN, and show that there is difference between the control cells and the micro-patterned cells.
AB - In order to develop the cell based robot, we presented a micro-mechanical force measurement system for the biological muscle actuators, which utilize glucose as a power source for potential application in digestive organ. The proposed system is composed of a micro-manipulator, a force transducer with a glass probe, a signal processor, an inverted microscope and video recoding system. Using this measurement system, the contractile force and frequency of the cardiac myocytes were measured in real time and the magnitudes of the contractile force of each cardiac myocyte under different conditions were compared. From the quantitative experimental results, we could estimate that the force of cardiac myocytes is about 20-40 μN, and show that there is difference between the control cells and the micro-patterned cells.
UR - http://www.scopus.com/inward/record.url?scp=33846908082&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33846908082
SN - 0780387406
SN - 9780780387409
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 5077
EP - 5080
BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Y2 - 1 September 2005 through 4 September 2005
ER -