TY - JOUR
T1 - Clinical features of metastatic tumors of the pancreas in Korea
T2 - A single-center study
AU - Yoon, Won Jae
AU - Ryu, Ji Kon
AU - Kim, Yong Tae
AU - Yoon, Yong Bum
AU - Kim, Sun Whe
AU - Kim, Woo Ho
PY - 2011/3
Y1 - 2011/3
N2 - Background/Aims: The purpose of this study was to examine the clinical features of metastatic tumors of the pancreas (MTPs) in Korea. Methods: A total of 53 cases (31 males) of pathologically proven MTPs were collected. Clinicopathological characteristics and patient outcomes were evaluated. Results: The median age at the diagnosis of the MTP was 60 years. The median interval between the diagnoses of primary malignancy and MTP was 2.2 years. Primary malignancies were renal cell carcinoma (RCC) (n=14), gastric cancer (n=11), colorectal cancer (n=5), lymphoma (n=4), non-small cell lung cancer (n=3), gastrointestinal stromal tumor (n=2), melanoma (n=2), small cell lung cancer (n=2), gallbladder cancer (n=2), hepatocellular carcinoma (n=1), thymic carcinoid (n=1), liposarcoma (n=1), cholangiocarcinoma (n=1), osteosarcoma (n=1), breast cancer (n=1), duodenal cancer (n=1), and ovarian cancer (n=1). The median survival after the diagnosis of MTP was 23.1 months. Multivariate analysis showed that prolonged survival was associated with RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment. Conclusions: MTPs can occur after a prolonged period from the primary diagnosis. RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment are associated with better prognosis.
AB - Background/Aims: The purpose of this study was to examine the clinical features of metastatic tumors of the pancreas (MTPs) in Korea. Methods: A total of 53 cases (31 males) of pathologically proven MTPs were collected. Clinicopathological characteristics and patient outcomes were evaluated. Results: The median age at the diagnosis of the MTP was 60 years. The median interval between the diagnoses of primary malignancy and MTP was 2.2 years. Primary malignancies were renal cell carcinoma (RCC) (n=14), gastric cancer (n=11), colorectal cancer (n=5), lymphoma (n=4), non-small cell lung cancer (n=3), gastrointestinal stromal tumor (n=2), melanoma (n=2), small cell lung cancer (n=2), gallbladder cancer (n=2), hepatocellular carcinoma (n=1), thymic carcinoid (n=1), liposarcoma (n=1), cholangiocarcinoma (n=1), osteosarcoma (n=1), breast cancer (n=1), duodenal cancer (n=1), and ovarian cancer (n=1). The median survival after the diagnosis of MTP was 23.1 months. Multivariate analysis showed that prolonged survival was associated with RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment. Conclusions: MTPs can occur after a prolonged period from the primary diagnosis. RCC as the primary malignancy, the patient being asymptomatic upon the diagnosis of MTP, the absence of extrapancreatic involvement, and surgery included in the treatment are associated with better prognosis.
KW - Neoplasm metastasis
KW - Neoplasms
KW - Pancreas
KW - Renal cell carcinoma
KW - Stomach neoplasms
UR - http://www.scopus.com/inward/record.url?scp=79952965082&partnerID=8YFLogxK
U2 - 10.5009/gnl.2011.5.1.61
DO - 10.5009/gnl.2011.5.1.61
M3 - Article
C2 - 21461074
AN - SCOPUS:79952965082
SN - 1976-2283
VL - 5
SP - 61
EP - 64
JO - Gut and Liver
JF - Gut and Liver
IS - 1
ER -