Clinical application of bone turnover markers in osteoporosis in Korea

So Young Park; Seong Hee Ahn; Jun Il Yoo; Youn Jee Chung; Yun Kyung Jeon; Byung Ho Yoon; Ha Young Kim; Seung Hun Lee; Jehoon Lee; Seongbin Hong

doi:10.11005/jbm.2019.26.1.19

Clinical application of bone turnover markers in osteoporosis in Korea

So Young Park, Seong Hee Ahn, Jun Il Yoo, Youn Jee Chung, Yun Kyung Jeon, Byung Ho Yoon, Ha Young Kim, Seung Hun Lee, Jehoon Lee, Seongbin Hong

Department of Orthopedic Surgery

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Bone turnover markers (BTMs) have important role in the management of osteoporosis. Recently the clinical application of BTMs has achieved significant progress and measurement of BTMs give us better understanding of pathogenesis of osteoporosis. However, the use of BTMs is still insufficient in Korea. We summarized the available methods and standard interval of the BTMs in Korea. Also we reviewed published literatures on pre-analytical variability in the measurement of BTMs and provided recommendations for standardized sample handling and patient preparation for reducing those pre-analytical variabilities. The clinical application of BTMs in patients with chronic kidney disease who have a higher fracture risk than the general population is summarized.

Original language	English
Pages (from-to)	19-24
Number of pages	6
Journal	Journal of Bone Metabolism
Volume	26
Issue number	1
DOIs	https://doi.org/10.11005/jbm.2019.26.1.19
State	Published - 1 Feb 2019

Bibliographical note

Publisher Copyright:
Copyright © 2019 The Korean Society for Bone and Mineral Research.

Keywords

Biomarkers
Bone remodeling
Bone turnover markers
Chronic kidney disease
Osteoporosis

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10.11005/jbm.2019.26.1.19

Cite this

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abstract = "Bone turnover markers (BTMs) have important role in the management of osteoporosis. Recently the clinical application of BTMs has achieved significant progress and measurement of BTMs give us better understanding of pathogenesis of osteoporosis. However, the use of BTMs is still insufficient in Korea. We summarized the available methods and standard interval of the BTMs in Korea. Also we reviewed published literatures on pre-analytical variability in the measurement of BTMs and provided recommendations for standardized sample handling and patient preparation for reducing those pre-analytical variabilities. The clinical application of BTMs in patients with chronic kidney disease who have a higher fracture risk than the general population is summarized.",

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AU - Park, So Young

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AU - Chung, Youn Jee

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AU - Yoon, Byung Ho

AU - Kim, Ha Young

AU - Lee, Seung Hun

AU - Lee, Jehoon

AU - Hong, Seongbin

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Clinical application of bone turnover markers in osteoporosis in Korea

Abstract

Bibliographical note

Keywords

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