cis-[(4R,5R)-4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane- N,N′](malonato-O,O′)platinum(II), an anticancer agent

Sang Woo Cho, Yongkee Cho, Dae Kee Kim, Whanchul Shin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


In the title compound, [Pt(C3H2O4)(C7H16N2O2)], the Pt atom is coordinated to two O and two N atoms in a square-planar arrangement. The two independent molecules, which have very similar structures, are approximately related by pseudo-twofold screw-axis symmetry. The six-membered chelate ring in the leaving ligand assumes a conformation intermediate between the half-chair and boat forms. The seven-membered ring in the carrier ligand assumes a twist-chair conformation and the oxolane ring assumes an envelope conformation. The crystal packing consists of extensive hydrogen-bonding networks which form two-dimensional molecular layers, and there are weak van der Waals interactions between these layers.

Original languageEnglish
Pages (from-to)653-654
Number of pages2
JournalActa Crystallographica Section C: Crystal Structure Communications
Issue number6
StatePublished - Jun 2000


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