TY - JOUR
T1 - cis-[(4R,5R)-4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane- N,N′](malonato-O,O′)platinum(II), an anticancer agent
AU - Cho, Sang Woo
AU - Cho, Yongkee
AU - Kim, Dae Kee
AU - Shin, Whanchul
PY - 2000/6
Y1 - 2000/6
N2 - In the title compound, [Pt(C3H2O4)(C7H16N2O2)], the Pt atom is coordinated to two O and two N atoms in a square-planar arrangement. The two independent molecules, which have very similar structures, are approximately related by pseudo-twofold screw-axis symmetry. The six-membered chelate ring in the leaving ligand assumes a conformation intermediate between the half-chair and boat forms. The seven-membered ring in the carrier ligand assumes a twist-chair conformation and the oxolane ring assumes an envelope conformation. The crystal packing consists of extensive hydrogen-bonding networks which form two-dimensional molecular layers, and there are weak van der Waals interactions between these layers.
AB - In the title compound, [Pt(C3H2O4)(C7H16N2O2)], the Pt atom is coordinated to two O and two N atoms in a square-planar arrangement. The two independent molecules, which have very similar structures, are approximately related by pseudo-twofold screw-axis symmetry. The six-membered chelate ring in the leaving ligand assumes a conformation intermediate between the half-chair and boat forms. The seven-membered ring in the carrier ligand assumes a twist-chair conformation and the oxolane ring assumes an envelope conformation. The crystal packing consists of extensive hydrogen-bonding networks which form two-dimensional molecular layers, and there are weak van der Waals interactions between these layers.
UR - http://www.scopus.com/inward/record.url?scp=0033726083&partnerID=8YFLogxK
U2 - 10.1107/S0108270100003577
DO - 10.1107/S0108270100003577
M3 - Article
C2 - 10902008
AN - SCOPUS:0033726083
SN - 0108-2701
VL - 56
SP - 653
EP - 654
JO - Acta Crystallographica Section C: Crystal Structure Communications
JF - Acta Crystallographica Section C: Crystal Structure Communications
IS - 6
ER -