Chemical sporulation and germination: Cytoprotective nanocoating of individual mammalian cells with a degradable tannic acid-FeIII complex

Juno Lee, Hyeoncheol Cho, Jinsu Choi, Doyeon Kim, Daewha Hong, Ji Hun Park, Sung Ho Yang, Insung S. Choi

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

Individual mammalian cells were coated with cytoprotective and degradable films by cytocompatible processes maintaining the cell viability. Three types of mammalian cells (HeLa, NIH 3T3, and Jurkat cells) were coated with a metal-organic complex of tannic acid (TA) and ferric ion, and the TA-FeIII nanocoat effectively protected the coated mammalian cells against UV-C irradiation and a toxic compound. More importantly, the cell proliferation was controlled by programmed formation and degradation of the TA-FeIII nanocoat, mimicking the sporulation and germination processes found in nature.

Original languageEnglish
Pages (from-to)18918-18922
Number of pages5
JournalNanoscale
Volume7
Issue number45
DOIs
StatePublished - 7 Dec 2015

Fingerprint

Dive into the research topics of 'Chemical sporulation and germination: Cytoprotective nanocoating of individual mammalian cells with a degradable tannic acid-FeIII complex'. Together they form a unique fingerprint.

Cite this