Chemical profiles and hypoglycemic activities of mulberry leaf extracts vary with ethanol concentration

Ji Yeon Kim, Hye In Chung, Kyeong Ok Jung, Ji Hyang Wee, Oran Kwon

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Five mulberry leaf extracts (water, 25, 50, 75, and 100% EtOH) were characterized for in vitro hypoglycemic activity and chemical profiles. According to chemical profiles obtained from 15Tesla Fourier transform ion cyclotron resonance mass spectrometry, water extracts contained more 1-deoxynojirimycin (DNJ) and fewer phytochemicals than other extracts. However, water extracts showed the highest inhibitory activity of glucose uptake. The degree of inhibition of α-glucosidase activity was similar for all extracts. The effect of mulberry leaf extracts on the glucose metabolism may be attributed to additional or cooperative effects of DNJ with other phytochemical compounds.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalFood Science and Biotechnology
Volume22
Issue number5
DOIs
StatePublished - Oct 2013

Keywords

  • α-glucosidase
  • 1-deoxynojirimycin
  • chemical profile
  • glucose uptake
  • mulberry leaf

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