Changes of serum cytokine profiles in Korean vivax malarial patients after chemotherapy

T. S. Kim, Y. B. Chung, H. J. Choi, H. J. Yang

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3 Scopus citations

Abstract

Changes of serum cytokines including interferon gamma inducible protein-10 (IP-10) chemokine were analyzed in a total of eight vivax malarial patients before and after chemotherapy by immunostaining for human cytokine antibodies attached to membranes. IP-10 was strongly reactive in the period before chloroquine/primaquine combined chemotherapy and disappeared after chemotherapy in all patients. Therefore, IP-10 chemokine may be of importance in the pathogenesis of vivax malaria and a good marker of a complete cure.

Original languageEnglish
Pages (from-to)183-185
Number of pages3
JournalParasitology Research
Volume100
Issue number1
DOIs
StatePublished - Dec 2006

Bibliographical note

Funding Information:
Acknowledgements We thank Mr. Je-Young Ryu for his technical support; this work was supported by grants from the Tropical and Endemic Parasitic Diseases Control Programme of the National Institute of Health (NIH 347-6111-211), Ministry of Health and Welfare, Republic of Korea.

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