Change in management and outcome of mechanical ventilation in Korea: a prospective observational study

Jae Kyeom Sim, Sang Min Lee, Hyung Koo Kang, Kyung Chan Kim, Young Sam Kim, Yun Seong Kim, Won Yeon Lee, Sunghoon Park, So Young Park, Ju Hee Park, Yun Su Sim, Kwangha Lee, Yeon Joo Lee, Jin Hwa Lee, Heung Bum Lee, Chae Man Lim, Won Il Choi, Ji Young Hong, Won Jun Song, Gee Young Suh

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background/Aims: There are few studies describing contemporary status of mechanical ventilation in Korea. We investigated changes in management and outcome of mechanical ventilation in Korea. Methods: International, prospective observational cohort studies have been conducted every 6 years since 1998. Korean intensive care units (ICUs) participated in 2010 and 2016 cohorts. We compared 2016 and 2010 Korean data. Results: Two hundred and twenty-six patients from 18 ICUs and 275 patients from 12 ICUs enrolled in 2016 and 2010, respectively. In 2016 compared to 2010, use of non-invasive ventilation outside ICU increased (10.2% vs. 2.5%, p = 0.001). Pressure-control ventilation was the most common mode in both groups. Initial tidal volume (7.1 mL/kg vs. 7.4 mL/kg, p = 0.372) and positive end-expiratory pressure (6 cmH2O vs. 6 cmH2O, p = 0.141) were similar, but peak pressure (22 cmH2O vs. 24 cmH2O, p = 0.011) was lower in 2016. More patients received sedatives (70.7% vs. 57.0%, p = 0.002) and analgesics (86.5% vs. 51.1%, p < 0.001) in 2016. The awakening (48.4% vs. 31.0%, p = 0.002) was more frequently attempted in 2016. The accidental extubation rate decreased to one tenth of what it was in 2010 (1.1% vs. 10.2%, p < 0.001). The ICU mortality did not change (31.4% vs. 35.6%, p = 0.343) but ICU length of stay showed a decreasing trend (9 days vs. 10 days, p = 0.054) in 2016. Conclusions: There were temporal changes in care of patients on mechanical ventilation including better control of pain and agitation, and active attempt of awakening.

Original languageEnglish
Pages (from-to)618-630
Number of pages13
JournalKorean Journal of Internal Medicine
Issue number3
StatePublished - 2022

Bibliographical note

Publisher Copyright:
© 2022 The Korean Association of Internal Medicine.


  • Agitation
  • Pain
  • Respiration, artificial
  • Ventilator weaning


Dive into the research topics of 'Change in management and outcome of mechanical ventilation in Korea: a prospective observational study'. Together they form a unique fingerprint.

Cite this