Chan-Lam coupling reaction of sulfamoyl azides with arylboronic acids for synthesis of unsymmetrical: N -arylsulfamides

Suk Young Won, Seo Eun Kim, Yong Ju Kwon, Inji Shin, Jungyeob Ham, Won Suk Kim

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

An efficient method was developed for the synthesis of unsymmetrical N-arylsulfamides using sulfamoyl azides and arylboronic acids in the presence of 10 mol% of copper chloride as the catalyst. The reaction was facilitated in MeOH in an open flask at room temperature. Unlike the coupling of sulfamides and boronic acids, the use of sulfamoyl azides was found to be beneficial with respect to the yield and reaction time.

Original languageEnglish
Pages (from-to)2493-2497
Number of pages5
JournalRSC Advances
Volume9
Issue number5
DOIs
StatePublished - 2019

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