TY - JOUR
T1 - CD 4+/CD56+ hematodermic neoplasm in infancy
T2 - Case report
AU - Suhng, Eun Ah
AU - Cheong, Seung Hyun
AU - Choi, Hae Young
AU - Myung, Ki Bum
AU - Choi, You Won
PY - 2011/11
Y1 - 2011/11
N2 - CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health ' Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this : case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.
AB - CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health ' Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this : case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.
KW - Blastic nk-cell lymphoma
KW - Cd4+/cd56+ hematodermic neoplasm
UR - http://www.scopus.com/inward/record.url?scp=84555196673&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84555196673
SN - 0494-4739
VL - 49
SP - 1017
EP - 1020
JO - Korean Journal of Dermatology
JF - Korean Journal of Dermatology
IS - 11
ER -