CD 4+/CD56+ hematodermic neoplasm in infancy: Case report

Eun Ah Suhng, Seung Hyun Cheong, Hae Young Choi, Ki Bum Myung, You Won Choi

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CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health ' Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this : case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.

Original languageEnglish
Pages (from-to)1017-1020
Number of pages4
JournalKorean Journal of Dermatology
Issue number11
StatePublished - Nov 2011


  • Blastic nk-cell lymphoma
  • Cd4+/cd56+ hematodermic neoplasm


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