Carotid intima-media thickness in Parkinson's disease

Jong Moon Lee, Kun Woo Park, Woo Keun Seo, Ho Park Moon, Changsu Han, Inho Jo, Ahn Jo Sangmee

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis.

Original languageEnglish
Pages (from-to)2446-2449
Number of pages4
JournalMovement Disorders
Issue number16
StatePublished - Dec 2007


  • Atherosclerosis
  • Intima-media thickness
  • Parkinson's disease


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