Abstract
Emerging systems biology aims at integrating the enormous amount of existing omics data in order to better understand their functional relationships at a whole systems level. These huge datasets can be obtained through advances in high-throughput, sensitive, precise, and accurate analytical instrumentation and technological innovation. Separation sciences play an important role in revealing biological processes at various omic levels. From the perspective of systems biology, CE is a strong candidate for high-throughput, sensitive data generation which is capable of tackling the challenges in acquiring qualitative and quantitative knowledge through a system-level study. This review focuses on the applicability of CE to systems-based analytical data at the genomic, transcriptomic, proteomic, and metabolomic levels.
Original language | English |
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Pages (from-to) | 97-110 |
Number of pages | 14 |
Journal | Electrophoresis |
Volume | 27 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2006 |
Keywords
- Capillary electrophoresis
- Omics
- Review
- Systems biology