Capillary electrophoresis at the omics level: Towards systems biology

C. V. Suresh Babu, Eun Joo Song, Sheikh Md Enayetul Babar, Mun Hyung Wi, Young Sook Yoo

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

Emerging systems biology aims at integrating the enormous amount of existing omics data in order to better understand their functional relationships at a whole systems level. These huge datasets can be obtained through advances in high-throughput, sensitive, precise, and accurate analytical instrumentation and technological innovation. Separation sciences play an important role in revealing biological processes at various omic levels. From the perspective of systems biology, CE is a strong candidate for high-throughput, sensitive data generation which is capable of tackling the challenges in acquiring qualitative and quantitative knowledge through a system-level study. This review focuses on the applicability of CE to systems-based analytical data at the genomic, transcriptomic, proteomic, and metabolomic levels.

Original languageEnglish
Pages (from-to)97-110
Number of pages14
JournalElectrophoresis
Volume27
Issue number1
DOIs
StatePublished - Jan 2006

Keywords

  • Capillary electrophoresis
  • Omics
  • Review
  • Systems biology

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