Cancer-specific therapeutic potential of resveratrol: Metabolic approach against hallmarks of cancer

Dong Hoon Suh; Mi Kyung Kim; Hee Seung Kim; Hyun Hoon Chung; Yong Sang Song

doi:10.31989/ffhd.v3i8.44

Cancer-specific therapeutic potential of resveratrol: Metabolic approach against hallmarks of cancer

Dong Hoon Suh, Mi Kyung Kim, Hee Seung Kim, Hyun Hoon Chung, Yong Sang Song

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Cancer hallmarks include evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis. Cancer cells undergo metabolic reprogramming and inevitably take advantage of glycolysis to meet the increased metabolic demand: rapid energy generation and macromolecular synthesis. Resveratrol, a polyphenolic phytoalexin, is known to exhibit pleiotropic anti-cancer effects most of which are linked to metabolic reprogramming in cancer cells. This review summarizes various anti-cancer effects of resveratrol in the context of cancer hallmarks in relation to metabolic reprogramming.

Original language	English
Pages (from-to)	332-343
Number of pages	12
Journal	Functional Foods in Health and Disease
Volume	3
Issue number	8
DOIs	https://doi.org/10.31989/ffhd.v3i8.44
State	Published - Aug 2013

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© 2013 Functional Foods in Health and Disease. All rights reserved.

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10.31989/ffhd.v3i8.44

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title = "Cancer-specific therapeutic potential of resveratrol: Metabolic approach against hallmarks of cancer",

abstract = "Cancer hallmarks include evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis. Cancer cells undergo metabolic reprogramming and inevitably take advantage of glycolysis to meet the increased metabolic demand: rapid energy generation and macromolecular synthesis. Resveratrol, a polyphenolic phytoalexin, is known to exhibit pleiotropic anti-cancer effects most of which are linked to metabolic reprogramming in cancer cells. This review summarizes various anti-cancer effects of resveratrol in the context of cancer hallmarks in relation to metabolic reprogramming.",

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AU - Chung, Hyun Hoon

AU - Song, Yong Sang

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AB - Cancer hallmarks include evading apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion and metastasis. Cancer cells undergo metabolic reprogramming and inevitably take advantage of glycolysis to meet the increased metabolic demand: rapid energy generation and macromolecular synthesis. Resveratrol, a polyphenolic phytoalexin, is known to exhibit pleiotropic anti-cancer effects most of which are linked to metabolic reprogramming in cancer cells. This review summarizes various anti-cancer effects of resveratrol in the context of cancer hallmarks in relation to metabolic reprogramming.

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ER -

Cancer-specific therapeutic potential of resveratrol: Metabolic approach against hallmarks of cancer

Abstract

Bibliographical note

UN SDGs

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