Abstract
Li-Fraumeni syndrome (LFS) is an inherited autosomal-dominant tumor-predisposition disorder caused by germline mutations in the TP53 tumor suppressor gene. Since patients with LFS are likely to develop therapy-related cancers, radiation therapy should be avoided if breast cancer is found in these individuals. Herein, we present a case of secondary breast cancer in an LFS patient after radiation and chemotherapy for the first diagnosed breast sarcoma.
| Original language | English |
|---|---|
| Pages (from-to) | 246-251 |
| Number of pages | 6 |
| Journal | Journal of the Korean Society of Radiology |
| Volume | 83 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2022 |
Bibliographical note
Publisher Copyright:© 2022 Korean Radiological Society. All right reserved.
Keywords
- Breast Neoplasms
- Li-Fraumeni Syndrome
- Sarcoma
- Second Primary