Boronate based fluorescence (ESIPT) probe for peroxynitrite

Adam C. Sedgwick, Xiaolong Sun, Gyoungmi Kim, Juyoung Yoon, Steven D. Bull, Tony D. James

Research output: Contribution to journalArticlepeer-review

104 Scopus citations


A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting" unit. The "protecting" unit of the probe is removed by peroxynitrite to "turn-on" ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

Original languageEnglish
Pages (from-to)12350-12352
Number of pages3
JournalChemical Communications
Issue number83
StatePublished - 2016


Dive into the research topics of 'Boronate based fluorescence (ESIPT) probe for peroxynitrite'. Together they form a unique fingerprint.

Cite this