Blood pressure control during chronic kidney disease progression

Seulbi Lee, Hyung Jung Oh, Eun Kyung Lee, Oesook Lee, Eunhee Ha, Seung Jung Kim, Duk Hee Kang, Kyu Bok Choi, Dong Ryeol Ryu

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

BACKGROUND: Hypertension is a major cause of end-stage renal disease, and blood pressure (BP) control is crucial in patients with chronic kidney disease (CKD). However, it is generally inadequately controlled in CKD patients. We investigated the prevalence of CKD patients with inadequate BP control and its related factors, based on the CKD stage. METHODS: We analyzed the health examination sample cohort database, which consisted of the randomly selected participants among all the citizens who received the health examination provided by National Health Insurance Service of Korea in 2012 and 2013. RESULTS: There were 27,350 CKD patients (7.9%) out of a total of 345,044 participants. As CKD stage progressed, there were more patients with poorly controlled hypertension compared to those with well-controlled hypertension. In addition, systolic BP increased with CKD stage progression, while diastolic BP was not significantly different. Age, female, body mass index, increased pulse pressure, CKD stage, and levels of fasting glucose, total cholesterol, hemoglobin, and proteinuria were significant factors associated with poor control of BP in hypertensive CKD patients. CONCLUSION: The proportion of CKD patients with poorly controlled hypertension significantly increased as CKD progressed, mainly associated with the increase in pulse pressure. However, future investigation for causal relationship between poorly controlled hypertension and its related factors is needed.

Original languageEnglish
Pages (from-to)610-616
Number of pages7
JournalAmerican Journal of Hypertension
Volume30
Issue number6
DOIs
StatePublished - 1 Jun 2017

Keywords

  • Blood pressure
  • Chronic kidney disease
  • Hypertension
  • Pulse pressure

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