Blood flow in simple microchannels

Wesley Chang, David Trebotich, Luke P. Lee, Dorian Liepmann

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

12 Scopus citations

Abstract

Development of medical micro-assay systems must be based on an understanding of blood flow mechanics at scales of tens to hundreds of microns. This study investigated the use of a simple power law model for blood flow of between 2.5 and 100 μ/min in channels with 200 × 60 μm cross-sections and the following configurations: straight, 90 degree bend, and sudden contraction from 200 to 100μm. Experimental measurements of pressure vs. flow rate for blood flow in these channels were compared to predictions generated by CFD simulations. The experiments and simulations were consistent in their predictions of the magnitude of hydrodynamic resistances of the channels and the slight non-linearity of pressure vs. flow in each of the channel configurations.

Original languageEnglish
Title of host publication1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings
EditorsAndre Dittmar, David Beebe
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages311-315
Number of pages5
ISBN (Electronic)0780366034, 9780780366039
DOIs
StatePublished - 2000
Event1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, MMB 2000 - Lyon, France
Duration: 12 Oct 200014 Oct 2000

Publication series

Name1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings

Conference

Conference1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, MMB 2000
Country/TerritoryFrance
CityLyon
Period12/10/0014/10/00

Bibliographical note

Publisher Copyright:
© 2000 IEEE.

Fingerprint

Dive into the research topics of 'Blood flow in simple microchannels'. Together they form a unique fingerprint.

Cite this