Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues

Sangjoon Mo, Dong Hwan Kim, Jong Hyun Lee, Je Won Park, Devi B. Basnet, Yeon Hee Ban, Young Ji Yoo, Shu Wei Chen, Sung Ryeol Park, Eun Ae Choi, Eunji Kim, Ying Yu Jin, Sung Kwon Lee, Ju Yeol Park, Yuan Liu, Mi Ok Lee, Keum Soon Lee, Sang Jun Kim, Dooil Kim, Byoung Chul ParkSang Gi Lee, Ho Jeong Kwon, Joo Won Suh, Bradley S. Moore, Si Kyu Lim, Yeo Joon Yoon

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Biochemistry, Genetics and Molecular Biology