TY - GEN
T1 - Bionano science and technology for innovative medicine
AU - Lee, Luke P.
PY - 2010
Y1 - 2010
N2 - It is our social responsibility to solve the problems of current healthcare systems by creating bionano science and technology. Convergence of biotechnology, nanotechnology, and information technology will establish precision biology and personalized medicine. This paper presents innovative biology and medicine via nanosatellites (i.e. optical nanoantennae) with triple functions of targeting, imaging and gene regulations, and biological application specific integrated circuits (BASICs). Nanosatellites provide spectroscopic imaging of living cells, molecular optogenetics (i.e. the remote control of gene regulation and protein expression), and therapeutic applications. BASICs are developed to accomplish precise and repeatable characterizations of cellular dynamics. These cellular BASICs are facilitating significant advancements in quantitative cell biology and the foundation for precision biology, cell reprogramming, high-speed biologic microprocessors, drug screening, molecular diagnostics, and personalized medicine.
AB - It is our social responsibility to solve the problems of current healthcare systems by creating bionano science and technology. Convergence of biotechnology, nanotechnology, and information technology will establish precision biology and personalized medicine. This paper presents innovative biology and medicine via nanosatellites (i.e. optical nanoantennae) with triple functions of targeting, imaging and gene regulations, and biological application specific integrated circuits (BASICs). Nanosatellites provide spectroscopic imaging of living cells, molecular optogenetics (i.e. the remote control of gene regulation and protein expression), and therapeutic applications. BASICs are developed to accomplish precise and repeatable characterizations of cellular dynamics. These cellular BASICs are facilitating significant advancements in quantitative cell biology and the foundation for precision biology, cell reprogramming, high-speed biologic microprocessors, drug screening, molecular diagnostics, and personalized medicine.
KW - Biophotonics
KW - Cell culture chip
KW - Microfluidics
KW - Molecular diagnostics
KW - Molecular optogenetics
KW - Nanoplasmonics
KW - Nanoprobes
KW - Nanoscope
KW - NASBA
KW - ONCOS
KW - Personalized medicine
KW - Quantitative biology
KW - Spectroscopic imaging
UR - http://www.scopus.com/inward/record.url?scp=79951825752&partnerID=8YFLogxK
U2 - 10.1109/IEDM.2010.5703276
DO - 10.1109/IEDM.2010.5703276
M3 - Conference contribution
AN - SCOPUS:79951825752
SN - 9781424474196
T3 - Technical Digest - International Electron Devices Meeting, IEDM
SP - 1.3.1-1.3.5
BT - 2010 IEEE International Electron Devices Meeting, IEDM 2010
T2 - 2010 IEEE International Electron Devices Meeting, IEDM 2010
Y2 - 6 December 2010 through 8 December 2010
ER -