Biomimetic micro-and nanofibrous scaffold for enhanced cartilage regeneration

I. K. Shim, J. H. Hwang, H. J. Ahn, S. H. Lee, M. C. Lee, S. J. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Biomimetic three-dimensional (3-D) micro-and nanofibrous scaffolds based on collagen nanofibers for chondrocyte culture and cartilage regeneration were investigated. PLGA solution and chitosan solution were homogenized using tween 80 as a emulsifier. PLGA/chitosan microfiber was fabricated by extruding the solution mixture into alkali methanol solution using 0.02mm nozzles. The morphology of fibrous matrices was examined by using a scanning electron microscope (SEM). Results show that micro-and nanofibrous matrix chondrocytes maintained spherical morphology and formed dense layer of cartilaginous tissue.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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