Bioinspired chemical inversion of L-amino acids to D-amino acids

Hyunjung Park; Mook Kim Kwan; Areum Lee; Sihyun Ham; Wonwoo Nam; Jik Chin

doi:10.1021/ja067724g

Bioinspired chemical inversion of L-amino acids to D-amino acids

Hyunjung Park, Mook Kim Kwan, Areum Lee, Sihyun Ham, Wonwoo Nam, Jik Chin

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

An organic receptor (1) that binds a wide variety of amino acids with the same sense of stereoselectivity (d/l ratio of about 10) has been developed. This receptor binds amino acids by formation of imines with internal resonance-assisted hydrogen bonds much as in imines formed between pyridoxal and amino acids. The internal resonance-assisted hydrogen bond is used to activate the bound amino acids and convert l-amino acids to d-amino acids.

Original language	English
Pages (from-to)	1518-1519
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	129
Issue number	6
DOIs	https://doi.org/10.1021/ja067724g
State	Published - 14 Feb 2007

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abstract = "An organic receptor (1) that binds a wide variety of amino acids with the same sense of stereoselectivity (d/l ratio of about 10) has been developed. This receptor binds amino acids by formation of imines with internal resonance-assisted hydrogen bonds much as in imines formed between pyridoxal and amino acids. The internal resonance-assisted hydrogen bond is used to activate the bound amino acids and convert l-amino acids to d-amino acids.",

author = "Hyunjung Park and Kwan, {Mook Kim} and Areum Lee and Sihyun Ham and Wonwoo Nam and Jik Chin",

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AU - Kwan, Mook Kim

AU - Lee, Areum

AU - Ham, Sihyun

AU - Nam, Wonwoo

AU - Chin, Jik

PY - 2007/2/14

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Bioinspired chemical inversion of L-amino acids to D-amino acids

Abstract

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