@article{c4e1fadc0797406289a6bec6a9580b39,
title = "Biofunctionalized AlGaN/GaN high electron mobility transistor for DNA hybridization detection",
abstract = "Label-free electrical detection of deoxyribonucleic acid (DNA) hybridization was demonstrated using an AlGaN/GaN high electron mobility transistor (HEMT) based transducer with a biofunctionalized gate. The HEMT DNA sensor employed the immobilization of amine-modified single strand DNA on the self-assembled monolayers of 11-mercaptoundecanoic acid. The sensor exhibited a substantial current drop upon introduction of complimentary DNA to the gate well, which is a clear indication of the hybridization. The application of 3 base-pair mismatched target DNA showed little change in output current characteristics of the transistor. Therefore, it can be concluded that our DNA sensor is highly specific to DNA sequences.",
author = "Resham Thapa and Siddharth Alur and Kyusang Kim and Fei Tong and Yogesh Sharma and Moonil Kim and Claude Ahyi and Jing Dai and {Wook Hong}, Jong and Michael Bozack and John Williams and Ahjeong Son and Amir Dabiran and Minseo Park",
note = "Funding Information: This project was funded by the United States Department of Agriculture (USDA) through Auburn University Detection and Food Safety Center (AUDFS). The authors would like to thank Dr. David Deen, SVT Associates, Inc., for his valuable comments to the manuscript and Dr. David Stanbury, Department of Chemistry and Biochemistry, Auburn University, for allowing us to use his UV-Vis spectrometer. ",
year = "2012",
month = jun,
day = "4",
doi = "10.1063/1.4727895",
language = "English",
volume = "100",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics",
number = "23",
}