Bioelectronic nose

Various studies on the olfactory sensor that mimicks a biological olfactory sensing mechanism have been carried out since the discovery of the smell sensing mechanism. The development of the olfactory biosensor has progressed well, especially with rapid advances in nanotechnology. The bioelectronic nose is defined as a smell sensing device that contains olfactory receptor proteins as a recognition element. The bioelectronic nose consists of two parts: one is a biological recognition element, called a primary transducer, which plays an important role in detecting ligands; and the other is a nanomaterial-based sensor platform, called a secondary transducer, which is the main part for enhancing the sensitivity of the bioelectronic nose. The bioelectronic nose can detect specific ligands with great selectivity and extremely high sensitivity. The development of the bioelectronic nose provides great potential for various applications, such as disease diagnosis, food quality assessment, fragrance and flavor evaluation, environmental and process monitoring, and smell sensing for public safety and security.