Biocatalytic conversion of methane to methanol as a key step for development of methane-based biorefineries

In Yeub Hwang, Seung Hwan Lee, Yoo Seong Choi, Si Jae Park, Jeong Geol Na, In Seop Chang, Choongik Kim, Hyun Cheol Kim, Yong Hwan Kim, Jin Won Lee, Eun Yeol Lee

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Methane is considered as a next-generation carbon feedstock owing to the vast reserves of natural and shale gas. Methane can be converted to methanol by various methods, which in turn can be used as a starting chemical for the production of value-added chemicals using existing chemical conversion processes. Methane monooxygenase is the key enzyme that catalyzes the addition of oxygen to methane. Methanotrophic bacteria can transform methane to methanol by inhibiting methanol dehydrogenase. In this paper, we review the recent progress made on the biocatalytic conversion of methane to methanol as a key step for methane-based refinery systems and discuss future prospects for this technology.

Original languageEnglish
Pages (from-to)1597-1605
Number of pages9
JournalJournal of Microbiology and Biotechnology
Volume24
Issue number12
DOIs
StatePublished - 2014

Keywords

  • Methane
  • Methane monooxygenase
  • Methanol
  • Methanotrophs
  • Natural gas
  • Shale gas

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