Bioactive natural products from the genus Salinospora: a review

Haerin Kim; Sohee Kim; Minju Kim; Chaeyoung Lee; Inho Yang; Sang Jip Nam

doi:10.1007/s12272-020-01288-1

Bioactive natural products from the genus Salinospora: a review

Haerin Kim, Sohee Kim, Minju Kim, Chaeyoung Lee, Inho Yang, Sang Jip Nam

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Actinomycetes are an important source for bioactive secondary metabolites. Among them, the genus Salinispora is one of the first salt obligatory marine species worldwide and is typically found in various types of substrates in tropical and subtropical marine environments including sediments and marine organisms. This genus produces a wide range of chemical scaffolds and bioactive compounds such as lomaiviticins, cyclomarins, rifamycins, salinaphthoquinones, and salinosporamides. This review arranged Salinispora derived secondary metabolites according to the three species that comprise the genus. Moreover, muta- and semi-synthesis analogs derived from salinosporamide were also described in this review.

Original language	English
Pages (from-to)	1230-1258
Number of pages	29
Journal	Archives of Pharmacal Research
Volume	43
Issue number	12
DOIs	https://doi.org/10.1007/s12272-020-01288-1
State	Published - Dec 2020

Bibliographical note

Publisher Copyright:
© 2020, The Pharmaceutical Society of Korea.

Keywords

Actinomycetes
Marine natural products
Salinispora
Salinispora arenicola
Salinispora pacifica
Salinispora tropica

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10.1007/s12272-020-01288-1

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title = "Bioactive natural products from the genus Salinospora: a review",

abstract = "Actinomycetes are an important source for bioactive secondary metabolites. Among them, the genus Salinispora is one of the first salt obligatory marine species worldwide and is typically found in various types of substrates in tropical and subtropical marine environments including sediments and marine organisms. This genus produces a wide range of chemical scaffolds and bioactive compounds such as lomaiviticins, cyclomarins, rifamycins, salinaphthoquinones, and salinosporamides. This review arranged Salinispora derived secondary metabolites according to the three species that comprise the genus. Moreover, muta- and semi-synthesis analogs derived from salinosporamide were also described in this review.",

keywords = "Actinomycetes, Marine natural products, Salinispora, Salinispora arenicola, Salinispora pacifica, Salinispora tropica",

author = "Haerin Kim and Sohee Kim and Minju Kim and Chaeyoung Lee and Inho Yang and Nam, {Sang Jip}",

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T1 - Bioactive natural products from the genus Salinospora

T2 - a review

AU - Kim, Haerin

AU - Kim, Sohee

AU - Kim, Minju

AU - Lee, Chaeyoung

AU - Yang, Inho

AU - Nam, Sang Jip

PY - 2020/12

Y1 - 2020/12

N2 - Actinomycetes are an important source for bioactive secondary metabolites. Among them, the genus Salinispora is one of the first salt obligatory marine species worldwide and is typically found in various types of substrates in tropical and subtropical marine environments including sediments and marine organisms. This genus produces a wide range of chemical scaffolds and bioactive compounds such as lomaiviticins, cyclomarins, rifamycins, salinaphthoquinones, and salinosporamides. This review arranged Salinispora derived secondary metabolites according to the three species that comprise the genus. Moreover, muta- and semi-synthesis analogs derived from salinosporamide were also described in this review.

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KW - Actinomycetes

KW - Marine natural products

KW - Salinispora

KW - Salinispora arenicola

KW - Salinispora pacifica

KW - Salinispora tropica

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DO - 10.1007/s12272-020-01288-1

M3 - Review article

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AN - SCOPUS:85096566336

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VL - 43

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EP - 1258

JO - Archives of Pharmacal Research

JF - Archives of Pharmacal Research

IS - 12

ER -

Bioactive natural products from the genus Salinospora: a review

Abstract

Bibliographical note

Keywords

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