Bio-functionalization of metal-organic frameworks by covalent protein conjugation

Suhyun Jung, Youngmee Kim, Sung Jin Kim, Tae Hwan Kwon, Seong Huh, Seongsoon Park

Research output: Contribution to journalArticlepeer-review

223 Scopus citations


Bioconjugation of functional proteins onto metal-organic frameworks (MOFs) has been achieved using activation of pendent linking groups of the organic linkers on the surface of MOFs. Fluorescent microscopy revealed successful conjugation of an enhanced fluorescent protein onto MOFs. In addition, Candida-antarctica-lipase-B-conjugated MOFs showed no loss of enantioselectivity and activity in transesterification of (±)-1-phenylethanol.

Original languageEnglish
Pages (from-to)2904-2906
Number of pages3
JournalChemical Communications
Issue number10
StatePublished - 21 Feb 2011


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